CN
Search Within
57-13-6
Applied Filters:
Keyword:'57-13-6'
Showing 31-60 of 211 results for "57-13-6" within Papers
S Ono et al.
Journal of experimental & clinical cancer research : CR, 21(3), 377-382 (2002-10-19)
Acetylation of core histones is closely linked to transcriptional activation of various genes. The acetylation levels of nucleosomal histones can be modified through a balance of histone acetyltransferases and deacetylases. To elucidate the role of histone acetylation in human gastric
J Thanusu et al.
Bioorganic & medicinal chemistry letters, 20(2), 713-717 (2009-12-17)
In the present work, a new series of bis hybrid heterocycle comprising both piperidine and thiohydantoin nuclei together namely 3-(3-alkyl-2,6-diarylpiperin-4-ylidene)-2-thioxoimidazolidin-4-ones 46-60 was synthesized by the treatment of the respective thiosemicarbazones 31-45 with chloroethyl acetate and anhydrous sodium acetate in refluxing
Fabio César Miranda Torricelli et al.
Neurourology and urodynamics, 30(8), 1522-1524 (2011-06-11)
To evaluate serum PSA levels of patients with spinal cord injury (SCI) submitted or not to CIC in comparison to those of the general population. We retrospectively studied 140 men with SCI admitted in our department from January 2005 to
B Kopf et al.
Bone marrow transplantation, 38(6), 407-412 (2006-09-05)
We conducted a prospective randomized clinical trial to assess the mobilizing efficacy of filgrastim, lenograstim and molgramostim following a disease-specific chemotherapy regimen. Mobilization consisted of high-dose cyclophosphamide in 45 cases (44%), and cisplatin/ifosfamide/etoposide or vinblastine in 22 (21%), followed by
S Lorenzen et al.
Annals of oncology : official journal of the European Society for Medical Oncology, 20(10), 1667-1673 (2009-06-25)
This study assessed the activity of the mAb cetuximab in combination with cisplatin and 5-fluorouracil (5-FU) in advanced esophageal squamous cell carcinoma. For a maximum of six 29-day cycles, patients received cisplatin 100 mg/m(2), day 1, plus 5-FU 1000 mg/m(2)
S Ono et al.
Journal of experimental & clinical cancer research : CR, 21(3), 377-382 (2002-10-19)
Acetylation of core histones is closely linked to transcriptional activation of various genes. The acetylation levels of nucleosomal histones can be modified through a balance of histone acetyltransferases and deacetylases. To elucidate the role of histone acetylation in human gastric
N Alami et al.
Journal of chemotherapy (Florence, Italy), 19(5), 546-553 (2007-12-13)
The aim of this study was to investigate the antiproliferative effects of C-1311 (Symadex), a member of the imidazoacridinone family, in human colorectal cancer cells. In the in vitro screen, C-1311 led to the most prominent growth inhibition in HT29
Ralph Carvalho et al.
Genes, chromosomes & cancer, 45(10), 967-975 (2006-07-27)
Diffuse-type gastric carcinomas (GCs) are often difficult to characterize because of contamination of tumor samples by surrounding normal tissue. As such, information regarding chromosomal aberrations in this subtype of GCs is limited. In this study, we used representational difference analysis
S M Wilhelm et al.
Proceedings of the National Academy of Sciences of the United States of America, 84(19), 6725-6729 (1987-10-01)
We have purified and determined the complete primary structure of human stromelysin, a secreted metalloprotease with a wide range of substrate specificities. Human stromelysin is synthesized in a preproenzyme form with a calculated size of 53,977 Da and a 17-amino
Sauzanne Khalilieh et al.
British journal of clinical pharmacology, 84(10), 2292-2302 (2018-06-22)
Tildrakizumab, an interleukin (IL)-23 inhibitor, is indicated for the treatment of moderate to severe chronic plaque psoriasis. Although tildrakizumab is not metabolized by, and does not alter, cytochrome P450 (CYP) expression in vitro, clinically significant pharmacokinetic effects through changes in
Christopher N Otis et al.
International journal of surgical pathology, 10(4), 237-245 (2002-12-20)
Correlation of loss of heterozygosity (LOH) of p53, BRCA1, VHL, and estrogen receptor (ER) genes with the expression of related protein products and morphologic features predictive of aggressive biologic behavior was investigated to determine the significance of LOH in these
C L McLaughlin et al.
Journal of dairy science, 95(8), 4363-4371 (2012-07-24)
The objectives of this study were to evaluate efficacy of a 2-dose regimen of ceftiofur crystalline free acid sterile suspension (CCFA-SS) for treatment of acute metritis in lactating dairy cows under field conditions and to provide additional safety and injection
Patrice Brassard et al.
Critical care medicine, 44(4), 755-763 (2015-11-21)
Sympathetic vasoconstriction regulates peripheral circulation and controls blood pressure, but sepsis is associated with hypotension. We evaluated whether apparent loss of sympathetic vasoconstrictor responsiveness relates to distended smooth muscles or to endotoxemia and/or hypoxia. Prospective descriptive study. Hospital research laboratory.
H Sun et al.
American journal of clinical pathology, 115(1), 32-38 (2001-02-24)
To determine the potential role of PTEN in the process of endometrial carcinogenesis, we examined a series of endometrial carcinoma and hyperplasia of the uterine corpus for the presence of a PTEN mutation. The entire coding region of the gene
Lai Meng Looi et al.
The Malaysian journal of pathology, 29(1), 33-35 (2007-06-01)
The unique ability of tumour cells to proliferate indefinitely is crucial to neoplastic progression as it allows these cells to express the aggressive properties of cancer without the censure of physiological ageing. This is in contrast to normal somatic cells
L M Biasucci et al.
Circulation, 99(16), 2079-2084 (1999-04-27)
A growing body of evidence suggests a role for inflammation in acute coronary syndromes. The aim of this study was to assess the role of proinflammatory cytokines, their time course, and their association with prognosis in unstable angina. We studied
Assaf Dotan et al.
Experimental eye research, 127, 190-195 (2014-08-12)
Our study demonstrates the effect of scleral cross-linking using riboflavin and ultraviolet-A radiation on the development of axial myopia in a rabbit model. Axial length of the eyeball was measured by A-scan ultrasound in 22 New Zealand white rabbits aged
Takashi Ueki et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 10(5), 1717-1725 (2004-03-12)
Biliary tract cancer is an uncommon malignancy with a poor survival rate. We evaluated p16 gene alteration as a prognostic marker for this disease. We studied p16 gene alterations by sequencing, methylation, and loss of heterozygosity of chromosome 9p in
Inmyoung Park et al.
Foods (Basel, Switzerland), 8(10) (2019-10-05)
Two thermophilic 1,4-α-glucan branching enzymes (GBEs), CbGBE from Caldicellulosiruptor bescii and PhGBE from Pyrococcus horikoshii, which belong to the glycoside hydrolase family 13 and 57 respectively, were cloned and expressed in Escherichia coli. Two GBEs were identified to have α-1,6
Basheer Peer Mohamed et al.
Developmental medicine and child neurology, 54(3), 274-277 (2012-01-25)
The aim of this study was to report a single-centre experience of flunarizine in childhood migraine with focus on safety and efficacy. We conducted a retrospective observational audit of 72 individuals (40 male, 32 female; mean age 13y; age range
Sameer Yaseen Al-Abdi et al.
Journal of clinical neonatology, 3(2), 76-88 (2014-07-16)
A considerable number of intraventricular hemorrhages (IVH) occur within the first hours of life (HOL). Temporality between IVH and its antecedents as well as a consistent definition of "early IVH" is lacking in a large and growing body of literature.
Fatih Mehmet Azik et al.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 17(1), 94-99 (2009-08-20)
The objective of this study was to elucidate the effects of tumor necrosis factor α (TNF-α), interleukin 1β (IL-1β), interleukin 2 (IL-2), interleukin 6 (IL-6), and interleukin 8 (IL-8) on the expression of soluble endothelial protein C receptor (sEPCR) in
A K Gedeon et al.
American journal of human genetics, 68(6), 1386-1397 (2001-05-12)
The X-linked form of spondyloepiphyseal dysplasia tarda (SEDL), a radiologically distinct skeletal dysplasia affecting the vertebrae and epiphyses, is caused by mutations in the SEDL gene. To characterize the molecular basis for SEDL, we have identified the spectrum of SEDL
Ann-Christine Ohlsson et al.
Logopedics, phoniatrics, vocology, 34(2), 60-66 (2009-03-25)
The objective of this study was to evaluate a Swedish version of the voice handicap index questionnaire (Sw-VHI). A total of 57 adult, dysphonic patients and 15 healthy controls completed the Sw-VHI and rated the degree of vocal fatigue and
Martin Reck et al.
The Lancet. Respiratory medicine, 7(5), 387-401 (2019-03-30)
The IMpower150 trial showed significant improvements in progression-free and overall survival with atezolizumab plus bevacizumab plus carboplatin plus paclitaxel (ABCP) versus the standard-of-care bevacizumab plus carboplatin plus paclitaxel (BCP) in chemotherapy-naive patients with non-squamous non-small-cell lung cancer. Here, we report
A Räisänen-Sokolowski et al.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 18(8), 735-743 (1999-10-08)
Mice with target gene deletions were used in an immunosuppressed, heterotopic mouse cardiac transplant model to investigate the effects of simultaneous deficiencies of ICAM-1 and P-selectin on late cardiac rejection. To determine the contribution of donor sources of ICAM-1 and
Jesús Hernández-Reyes et al.
Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion, 64(6 Pt 2), 604-608 (2013-04-19)
In a 30-year period in a single institution, 23 cases of systemic immunoglobulin light chain amyloidosis (AL) were identified, within a group of 1,388 individuals with some form of a hematological malignancy. AL is 14 times less frequent in Mexico
Madhur D Shastri et al.
PloS one, 10(6), e0128803-e0128803 (2015-06-06)
Enoxaparin, a low-molecular-weight heparin, is known to possess anti-inflammatory properties. However, its clinical exploitation as an anti-inflammatory agent is hampered by its anticoagulant effect and the associated risk of bleeding. The aim of the current study was to examine the
Elena López-Knowles et al.
Cancer research, 66(15), 7401-7404 (2006-08-04)
Bladder tumors constitute a very heterogeneous disease. Superficial tumors are characterized by a high prevalence of FGFR3 mutations and chromosome 9 alterations. High-grade and muscle-invasive tumors are characterized by Tp53 mutations and aneuploidy. We have analyzed the sequence of exons
L Wang et al.
Annals of clinical biochemistry, 44(Pt 1), 57-62 (2007-02-03)
Autoantibodies against the p53 proteins (p53 Abs) can be detected in the serum, ascites, saliva and pleural effusions of various malignant patients. It is suggested that p53 Abs in pleural effusions might have some value for tumour diagnosis, prognosis or
Page 2 of 8