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Showing 1-30 of 37 results for "746371" within Papers
Anke de Vries et al.
Investigative radiology, 50(4), 297-304 (2015-01-01)
The objective of this study was to investigate the feasibility and the accuracy of spectral computed tomography (spectral CT) to determine the tissue concentrations and localization of high-attenuation, iodine-based contrast agents in mice. Iodine tissue concentrations determined with spectral CT
Zachary C Kennedy et al.
Langmuir : the ACS journal of surfaces and colloids, 31(46), 12742-12752 (2015-10-27)
The interactions of nanoparticles with biomolecules, surfaces, or other nanostructures are dictated by the nanoparticle's surface chemistry. Thus, far, shortcomings of syntheses of nanoparticles with defined ligand shell architectures have limited our ability to understand how changes in their surface
Zhibo Liu et al.
Molecular pharmaceutics, 12(3), 974-982 (2015-01-30)
Bradykinin B1 receptor (B1R) is involved in pain and inflammation pathways and is upregulated in inflamed tissues and cancer. Due to its minimal expression in healthy tissues, B1R is an attractive target for the development of therapeutic agents to treat
Stefan Opitz et al.
Analytical and bioanalytical chemistry, 407(4), 1107-1118 (2014-11-27)
Triton X-100 has been widely used in many analytical and preparative protocols for a long time. Nevertheless, mass spectrometry, chromatographic separation, and spectrophotometric readout may be considerably hampered by this detergent due to signal suppression, complex formation, and high blank
Angela Lombardi et al.
The Journal of clinical endocrinology and metabolism, 100(1), E1-10 (2014-10-09)
Amiodarone (AMIO) is one of the most effective antiarrhythmic drugs available; however, its use is limited by a serious side effect profile, including thyroiditis. The mechanisms underlying AMIO thyroid toxicity have been elusive; thus, identification of novel approaches in order
Prakash Ramalingam et al.
Pharmaceutical research, 32(2), 389-402 (2014-08-02)
Solid lipid nanoparticles (SLNs) have been proposed as a colloidal carrier system that could enhance the oral bioavailability of curcumin. However, a burst release of the loaded drug, which occurs in acidic environments, has been a main obstacle to the
Panayota Kolypetri et al.
Journal of immunology (Baltimore, Md. : 1950), 193(1), 96-101 (2014-06-01)
Enhanced iodide ingestion is known to accelerate the incidence and severity of spontaneous autoimmune thyroiditis [iodide-accelerated spontaneous autoimmune thyroiditis (ISAT)] in NOD.H2(h4) mice. CD4+ cells are required for the development and maintenance of ISAT, but their target epitopes remain unknown.
Hyojung Cha et al.
ACS applied materials & interfaces, 6(18), 15774-15782 (2014-08-26)
The molecular packing structures of two conjugated polymers based on alkoxy naphthalene, one with cyano-substituents and one without, have been investigated to determine the effects of electron-withdrawing cyano-groups on the performance of bulk-heterojunction solar cells. The substituted cyano-groups facilitate the
Kerstin Knoop et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 56(4), 600-606 (2015-03-07)
The tumor-homing property of mesenchymal stem cells (MSCs) allows targeted delivery of therapeutic genes into the tumor microenvironment. The application of sodium iodide symporter (NIS) as a theranostic gene allows noninvasive imaging of MSC biodistribution and transgene expression before therapeutic
Vinod Vellora Thekkae Padil et al.
Journal of agricultural and food chemistry, 63(14), 3757-3765 (2015-03-24)
Esterifications of the tree-based gum, gum karaya (GK), using dodecenylsuccinic anhydride (DDSA) were carried out in aqueous solutions. GK was deacetylated using alkali treatment to obtain deacetylated gum karaya (DGK). The DGK and its DDSA derivative were characterized using gel
Bert Wouters et al.
Journal of chromatography. A, 1370, 63-69 (2014-12-03)
The gradient-performance limits of capillary ion chromatography have been assessed at maximum system pressure (34.5 MPa) using capillary columns packed with 4.1 μm macroporous anion-exchange particles coated with 65 nm positively-charged nanobeads. In analogy to the van-Deemter curve, the gradient
Zi-Ming Zhao et al.
Chemical & pharmaceutical bulletin, 63(3), 180-186 (2015-03-12)
Two types of amphoteric calix[n]arene carboxylic acid (CnCA) derivative, i.e., calix[6]arene hexa-carboxylic acid (C6HCA) and calix[8]arene octo-carboxylic acid (C8OCA), were synthesized by introducing acetoxyls into the hydroxyls of calix[n]arene (n=6, 8). C6HCA and C8OCA nanoparticles (NPs) were prepared successfully using
Małgorzata Wolny et al.
Endokrynologia Polska, 58(6), 512-521 (2008-01-22)
The sodium iodide symporter, called also the NIS protein is responsible for iodine trapping to the cell what is significant for the thyroid function. Identified and described for the first time in 1996 NIS protein is the matter of interest
Nan Zhang et al.
Pharmaceutical research, 31(9), 2326-2334 (2014-03-07)
To evaluate the therapeutic efficacy of dexamethasone (DM) and methotrexate (MTX) entrapped within polysialic acid (PSA)-trimethyl chitosan (TMC) nanoparticles using an in vitro model of rheumatoid arthritis (RA). The loading capacity of the PSA-TMC nanoparticles was determined. An RA in
Yayoi S Kikkawa et al.
Journal of translational medicine, 12, 280-280 (2014-10-05)
A cochlear implant (CI) is an artificial hearing device that can replace a damaged cochlea. The present study examined the use of growth factor-eluting gelatin hydrogel coatings on the electrodes to minimize inner ear trauma during electrode insertion. Insulin-like growth
Charles A Pickering et al.
Health physics, 107(2 Suppl 2), S163-S165 (2014-06-21)
Initial radiation exposure levels X (0) at 1 m from the navel of thyroid cancer patients were measured for 165 individuals at the time of ingestion. Some 61 patients had previously signed informed consent so only those patients could be
Marlein Miranda Cona et al.
International journal of oncology, 44(3), 819-829 (2013-12-25)
Iodine-131‑labeled monoiodohypericin (131I‑Hyp) is a necrosis avid compound used as a complementary anticancer agent. Herein, the biodistribution in rats with re-perfused partial liver infarction (RPLI) was used to estimate its human internal radiation dosimetry. Iodine-123‑labeled monoiodohypericin (123I-Hyp) as a safer
Fabien Hyafil et al.
Molecular imaging, 14, 433-442 (2015-10-04)
[18F]ML-10 (2-(5-fluoro-pentyl)-2-methylmalonic acid) is a positron emission tomography (PET) radiotracer that accumulates in cells presenting apoptosis-specific membrane alterations. The aim of this study was to test whether [18F]ML-10 allows for the detection of apoptotic cells located in atherosclerotic plaques in
Angel T Chan et al.
Biomaterials, 73, 1-11 (2015-09-18)
Cell death due to anoikis, necrosis and cell egress from transplantation sites limits functional benefits of cellular cardiomyoplasty. Cell dissociation and suspension, which are a pre-requisite for most cell transplantation studies, lead to depression of cellular metabolism and anoikis, which
Kengo Kanazaki et al.
Nanomedicine : nanotechnology, biology, and medicine, 11(8), 2051-2060 (2015-08-05)
Photoacoustic (PA) imaging is a promising imaging modality that provides biomedical information with high sensitivity and resolution. Iron oxide nanoparticles (IONPs) have been regarded as remarkable PA contrast agents because of their low toxicity and biodegradable properties. However, IONP delivery
Aiwen Huang et al.
Drug delivery, 21(5), 388-396 (2013-11-06)
In this study both N-trimethyl chitosan chloride (TMC) and oligoarginine (Arg8) were utilized to modify liposomes as the multifunctional carriers (TMC-Arg8-Lips) for enhancing the oral absorption of salmon calcitonin. Two permeation enhancers with positive charges were sequentially adsorbed on the
Michael A Klufas et al.
Retina (Philadelphia, Pa.), 35(3), 508-520 (2014-09-25)
To evaluate the feasibility and clinical utility of a novel noncontact scanning laser ophthalmoscope-based ultra-widefield indocyanine green angiographic system. Ultra-widefield indocyanine green angiographic images were captured using a modified Optos P200Tx that produced high-resolution images of the choroidal vasculature with
Mohamed Touati et al.
Leukemia & lymphoma, 56(2), 332-341 (2014-04-29)
Finding new prognostic factors to identify patients with Hodgkin lymphoma (HL) at risk of treatment resistance or relapse remains challenging in daily practice. We evaluated the relationship between CD68 expression, interim positron emission tomography (iPET) results and outcome in 158
Astrid Subrizi et al.
Pharmaceutical research, 32(1), 211-221 (2014-07-18)
To measure the cytoprotective effects of rhHsp70 against oxidative stress and study its cellular uptake, intracellular and intraocular distribution in the retinal pigment epithelium. Human retinal pigment epithelial cells (ARPE-19) were pre-treated with rhHsp70 for 24 h, 48 h, and 72 h before
Takuro Isoda et al.
Clinical nuclear medicine, 39(8), 680-684 (2014-07-01)
Many cases of unexpected radioiodine uptake have been reported, including physiological uptake in healthy tissue and in both benign and malignant nonthyroidal lesions. However, iodine uptake in the uterus has not been well assessed. In this article, we systemically analyzed
Annukka M Kallinen et al.
Molecular pharmaceutics, 11(8), 2876-2886 (2014-07-01)
The use of nanoparticle carriers for the sustained release of cytotoxic drugs in cancer therapy can result in fewer adverse effects and can thus be of great benefit for the patient. Recently, a novel nanocomposite, prepared by the encapsulation of
Ada Repetto-Llamazares et al.
Anticancer research, 34(7), 3263-3269 (2014-07-02)
We herein report a comparison of the radiolabels 177Lu and 125I bound to the monoclonal antibody HH1 that targets the CD37 antigen expressed on non-Hodgkin B-cell lymphomas. Mixtures of 177Lu and 125I-labeled HH1 antibody were co-injected into nude mice carrying
[How does iodine reach the thyroid gland? Recent studies of the sodium-iodide symporter].
J Köhrle et al.
Der Internist, 39(6), 560-565 (1998-07-25)
Evelien Wynendaele et al.
PloS one, 10(11), e0142071-e0142071 (2015-11-05)
Bacteria communicate with each other by the use of signaling molecules, a process called 'quorum sensing'. One group of quorum sensing molecules includes the oligopeptides, which are mainly produced by Gram-positive bacteria. Recently, these quorum sensing peptides were found to
Hao Lou et al.
Pharmaceutical development and technology, 19(5), 548-555 (2013-06-15)
The purpose of this study is to evaluate the influence of sodium iodide, sodium chloride and sodium sulfate on the formation efficiency of sulfamerazine nanocrystals by wet ball milling. Sulfamerazine was milled using zirconium oxide beads in a solution containing
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