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Showing 1-30 of 2856 results for "861677" within Papers
Dongchao Xie et al.
Food research international (Ottawa, Ont.), 125, 108635-108635 (2019-09-27)
Storage has a dramatic influence on the chemical composition, sensory qualities, biological activity, and therefore the commercial value of white tea. In this study, the metabolites in white teas stored for 1, 3, 7, and ≥ 10 years were comprehensively compared by a
Ye Kuang et al.
International journal of molecular sciences, 19(6) (2018-06-03)
Chemical injury is partly due to free radical lipid peroxidation, which can induce oxidative stress and produce a large number of reactive oxygen species (ROS). Oxaloacetic acid is an important intermediary in the tricarboxylic acid cycle (TCA cycle) and participates
Dae-Hee Lee et al.
Autophagy, 14(11), 1870-1885 (2018-07-07)
Macroautophagy is induced under various stresses to remove cytotoxic materials, including misfolded proteins and their aggregates. These protein cargoes are collected by specific autophagic receptors such as SQSTM1/p62 (sequestosome 1) and delivered to phagophores for lysosomal degradation. To date, little
William S Sheridan et al.
Annals of biomedical engineering, 42(10), 2029-2038 (2014-07-06)
The goal of this study was to promote rapid repopulation of the medial layer of decellularized tissues for use as vascular grafts. We utilized a combined approach of biochemical and mechanical stimuli to enhance repopulation of decellularized porcine arterial tissue.
Michaela Libiaková et al.
PloS one, 9(8), e104424-e104424 (2014-08-26)
The trap of the carnivorous plant Venus flytrap (Dionaea muscipula) catches prey by very rapid closure of its modified leaves. After the rapid closure secures the prey, repeated mechanical stimulation of trigger hairs by struggling prey and the generation of
Ming Bai et al.
Saudi journal of biological sciences, 26(3), 569-576 (2019-03-23)
Explore the possible protective effect of Sargentodoxa cuneata total phenolic acids on cerebral ischemia reperfusion injury rats. Focal cerebral ischemia reperfusion rats model were established by linear thrombus. Nimodipine group, Naoluotong group, the high, middle and low dose of Sargentodoxa
Suellen Silva de Almeida et al.
Food chemistry, 333, 127473-127473 (2020-07-14)
This study aimed at investigating two strategies to enhance the bioaccessibility of phenolic compounds from whole-wheat breads: enzymatic bioprocessing and addition of green coffee infusion. Although both strategies had a significant effect on increasing the contents of total soluble phenolic
Vittoria Matafora et al.
EMBO reports, 21(9), e50446-e50446 (2020-08-05)
Melanoma progression is generally associated with increased transcriptional activity mediated by the Yes-associated protein (YAP). Mechanical signals from the extracellular matrix are sensed by YAP, which then activates the expression of proliferative genes, promoting melanoma progression and drug resistance. Which
Amy E Danson et al.
Biology, 9(10) (2020-10-24)
Chlamydia pneumoniae is a Gram-negative bacterium responsible for a number of human respiratory diseases and linked to some chronic inflammatory diseases. The major outer membrane protein (MOMP) of Chlamydia is a conserved immunologically dominant protein located in the outer membrane
S Azinas et al.
Nanoscale, 10(16), 7769-7779 (2018-04-17)
The protection of the viral genome during extracellular transport is an absolute requirement for virus survival and replication. In addition to the almost universal proteinaceous capsids, certain viruses add a membrane layer that encloses their double-stranded (ds) DNA genome within
Yong-Hee Cho et al.
Cell communication and signaling : CCS, 18(1), 38-38 (2020-03-08)
Cancer stem cells (CSCs), the major driver of tumorigenesis, is a sub-population of tumor cells responsible for poor clinical outcomes. However, molecular mechanism to identify targets for controlling CSCs is poorly understood. Gene Set Enrichment Analyses (GSEA) of Wnt/β-catenin and
Marlon-Schylor L le Roux et al.
Frontiers in plant science, 11, 1053-1053 (2020-08-08)
Random mutagenesis was applied to produce a new wheat mutant (RYNO3926) with superior characteristics regarding tolerance to water deficit stress induced at late booting stage. The mutant also displays rapid recovery from water stress conditions. Under water stress conditions mutant
Theeraporn Pulpipat et al.
Vaccines, 8(2) (2020-04-09)
Francisella noatunensis subsp. orientalis (Fno), an intracellular bacterium, causes systemic granulomatous diseases, resulting in high mortality and huge economic losses in Taiwanese tilapia farming. In this study, we tested the efficacy of a formalin-killed Fno vaccine in cultured tilapia. Fno
John F Valliere-Douglass et al.
Journal of pharmaceutical sciences, 104(2), 652-665 (2014-12-04)
We report that a unique type of chemical modification occurs on lyophilized proteins. Freeze-dried mAbs and antibody-drug conjugates (ADCs) can be covalently modified with buffer and excipient molecules on the side chains of Glu, Asp, Thr, and Ser amino acids
Prakitchai Chotewutmontri et al.
PLoS genetics, 14(8), e1007555-e1007555 (2018-08-07)
Plants and algae adapt to fluctuating light conditions to optimize photosynthesis, minimize photodamage, and prioritize energy investments. Changes in the translation of chloroplast mRNAs are known to contribute to these adaptations, but the scope and magnitude of these responses are
M S Budamagunta et al.
Cytoskeleton (Hoboken, N.J.), 75(1), 3-11 (2017-11-07)
Proteins predicted to be composed of large stretches of coiled-coil structure have often proven difficult to crystallize for structural determination. We have successfully applied EPR spectroscopic techniques to the study of the structure and assembly of full-length human vimentin assembled
Kiran Jadhav et al.
Materials science & engineering. C, Materials for biological applications, 93, 664-670 (2018-10-03)
Gold nanoparticles have been extensively used in diagnostics, biomedical imaging, and drug delivery owing to simple method of synthesis and versatile surface functionalization. Present investigation aims to evaluate the osteoinductive property of Salacia chinensis (SC) mediated gold nanoparticles (GNPs) for
Nicole Willems et al.
Arthritis research & therapy, 17, 137-137 (2015-05-28)
Strategies for biological repair and regeneration of the intervertebral disc (IVD) by cell and tissue engineering are promising, but few have made it into a clinical setting. Recombinant human bone morphogenetic protein 7 (rhBMP-7) has been shown to stimulate matrix
head-bent resistant Hsc70 variants show reduced Hsp40 affinity and altered protein folding activity.
Katharina Papsdorf et al.
Scientific reports, 9(1), 11955-11955 (2019-08-20)
The molecular chaperone Hsc70 performs essential tasks by folding proteins. Hsc70 is driven by the hydrolysis of ATP and tuned by the association with various co-chaperones. One such cofactor is the nematode nucleotide exchange factor UNC-23, whose mutation disrupts muscle
Arunkumar Krishnan et al.
BMC evolutionary biology, 19(1), 96-96 (2019-04-27)
Animals have a greater diversity of signalling pathways than their unicellular relatives, consistent with the evolution and expansion of these pathways occurring in parallel with the origin of animal multicellularity. However, the genomes of sponges and ctenophores - non-bilaterian basal
Laura C Motta et al.
The journal of physical chemistry. A, 124(14), 2842-2853 (2020-03-05)
The photochemical reduction of Hg(II) is an important pathway in the environmental Hg cycle because it competes with Hg methylation and potentially limits the formation of bioaccumulative methylmercury. Hg stable isotope systematics have proven to be an effective tool for
Muhammad Idrees et al.
International journal of molecular sciences, 20(23) (2019-12-08)
The PPARs (peroxisome proliferator-activated receptors) play critical roles in the regulation of lipid and glucose metabolism. PPARδ, a member of the PPARs family, is associated with decreased susceptibility to ectopic lipid deposition and is implicated in the regulation of mitochondrial
Remy Romanet et al.
Molecules (Basel, Switzerland), 24(7) (2019-04-10)
The DPPH (2,2-Diphenyl-1-picrylhydrazyl) assay is an easy and efficient method commonly used to determine the antioxidant capacity of many food matrices and beverages. In contrast with red wines, white wines are poorer in antioxidant polyphenolics, and the more hydrophilic sulfur-containing
Study of the physiological mechanism of delaying cucumber senescence by wheat intercropping pattern.
Huimin Liu et al.
Journal of plant physiology, 234-235, 154-166 (2019-03-01)
This paper investigates the physiological mechanism of the effect of delaying cucumber senescence on protein levels under the experimental model of monoculture and wheat intercropping. We analyzed cucumber roots for differential protein expression, and protein types were identified by core
Zoya Zaheer et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 182, 87-94 (2017-04-14)
The work describes an easy seedless competitive chemical reduction method for the synthesis of Ag@Au/Ag bimetallic nanoparticles by mixing AgNO
Alexander C Graf et al.
Molecular & cellular proteomics : MCP, 18(6), 1036-1053 (2019-03-10)
Staphylococcus aureus is the causative agent of various biofilm-associated infections in humans causing major healthcare problems worldwide. This type of infection is inherently difficult to treat because of a reduced metabolic activity of biofilm-embedded cells and the protective nature of
Léa Chaskiel et al.
Brain, behavior, and immunity, 81, 560-573 (2019-07-17)
A reduction in food intake is commonly observed after bacterial infection, a phenomenon that can be reproduced by peripheral administration of Gram-negative bacterial lipopolysaccharide (LPS) or interleukin-1beta (IL-1β), a pro-inflammatory cytokine released by LPS-activated macrophages. The arcuate nucleus of the
Borja Mateos et al.
Journal of molecular biology, 432(9), 3093-3111 (2019-12-04)
Intrinsically disordered proteins (IDPs) carry out many biological functions. They lack a stable three-dimensional structure, but rather adopt many different conformations in dynamic equilibrium. The interplay between local dynamics and global rearrangements is key for their function. In IDPs, proline
Sheldon Rowan et al.
Free radical biology & medicine, 150, 75-86 (2020-02-19)
Age-related macular degeneration (AMD) is a major blinding disease, affecting over 14% of the elderly. Risk for AMD is related to age, diet, environment, and genetics. Dietary modulation of AMD risk is a promising treatment modality, but requires appropriate animal
Soumya Paul et al.
Molecular immunology, 99, 9-18 (2018-04-13)
Development of a safe and efficacious vaccine for brucellosis is a long standing challenge for scientists. Recognizing potential antigens towards developing vaccine candidate is crucial. Omp25c, a porin protein of Brucella, is a paralog of two previously identified promising vaccine
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