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Showing 1-30 of 193 results for "97336" within Papers
Valerio Leoni et al.
Clinical chemistry and laboratory medicine, 42(2), 186-191 (2004-04-06)
24S-Hydroxycholesterol (24OHC) and 27-hydroxycholesterol (27OHC) are two structurally similar oxysterols of different origins--the former almost exclusively formed in the brain and the latter formed to a lesser extent in the brain than in most other organs. HYPOTHESIS TO BE TESTED:
Livan Delgado-Roche et al.
Journal of cardiovascular pharmacology, 61(2), 160-165 (2012-12-12)
Atherosclerosis is a major cause of death in the Western World. It is known that Lipofundin 20% induces atherosclerotic lesions, whereas ozone at low doses has been satisfactorily used in the prevention of oxidative stress-associated pathologies, such as coronary artery
M J Peterson et al.
Metabolism: clinical and experimental, 35(4 Suppl 1), 93-95 (1986-04-01)
Increased flux of glucose through the polyol pathway with resultant resultant accumulation of tissue sorbitol is implicated in the pathogenesis of the chronic complications of diabetes. Sorbinil is a potent inhibitor of aldose reductase (the first enzyme in the polyol
Ziv Harel et al.
The American journal of medicine, 126(3), 264-264 (2013-01-17)
Sodium polystyrene sulfonate (Kayexalate; Sanofi-Aventis, Paris, France) is a cation-exchange resin routinely used in the management of hyperkalemia. However, its use has been associated with colonic necrosis and other fatal gastrointestinal adverse events. Although the addition of sorbitol to sodium
Camille Desgrouas et al.
Malaria journal, 13, 327-327 (2014-08-26)
New classes of anti-malarial drugs are needed to control the alarming Plasmodium falciparum resistance toward current anti-malarial therapy. The ethnopharmacological approach allows the discovery of original chemical structures from the vegetable biodiversity. Previous studies led to the selection of a
Joshua Russell et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(22), 8269-8274 (2014-05-21)
All terrestrial animals must find a proper level of moisture to ensure their health and survival. The cellular-molecular basis for sensing humidity is unknown in most animals, however. We used the model nematode Caenorhabditis elegans to uncover a mechanism for
M A Lovell et al.
Archives of neurology, 58(3), 392-396 (2001-03-20)
Markers of oxidative stress are increased in cerebrospinal fluid (CSF) of patients with Alzheimer disease (AD), although none of those reported are appropriate diagnostic markers because of the overlap between patients with AD and control subjects. To determine the ratio
I Thorild et al.
European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 13(6), 305-307 (2012-12-14)
To evaluate the long-term outcome of a mother-child project in which mothers (n=173) with high counts of salivary mutans streptococci were randomly assigned to daily chewing gums containing xylitol (A), chlorhexidine/ xylitol/sorbitol (B), or sodium fluoride/xylitol/sorbitol (C) for one year
Relationship between glutathione and sorbitol concentrations in erythrocytes from diabetic patients.
E Ciuchi et al.
Metabolism: clinical and experimental, 45(5), 611-613 (1996-05-01)
Red blood cell (RBC) concentrations of sorbitol and reduced glutathione (GSH) were evaluated in 29 type 11 diabetic subjects and eight normal controls. In erythrocytes from diabetic subjects, sorbitol levels were higher (18.7 +/- 1.33 v 11.2 +/- 0.7 nmol/g
J A Molina et al.
Journal of neural transmission (Vienna, Austria : 1996), 109(7-8), 1035-1044 (2002-07-12)
Thiamine is an essential cofactor for several important enzymes involved in brain oxidative metabolism, such as the alpha-ketoglutarate dehydrogenase complex (KGDHC), pyruvate-dehydrogenase complex (PDHC), and transketolase. Some investigators reported decreased thiamine-diphosphate levels and decreased activities of KGDHC, pyruvate-dehydrogenase complex and
Hiroko Asahi et al.
BMC microbiology, 14, 167-167 (2014-06-26)
Malaria continues to be a devastating disease. The elucidation of factors inducing asexual growth versus arrest of Plasmodium falciparum can provide information about the development of the parasite, and may help in the search for novel malaria medication. Based on
Reddy Ranjith K Sama et al.
Journal of cellular physiology, 228(11), 2222-2231 (2013-04-30)
FUsed in Sarcoma/Translocated in LipoSarcoma (FUS/TLS or FUS) has been linked to several biological processes involving DNA and RNA processing, and has been associated with multiple diseases, including myxoid liposarcoma and amyotrophic lateral sclerosis (ALS). ALS-associated mutations cause FUS to
A Patrizi et al.
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 147(6 Suppl 1), 1-8 (2013-01-18)
Pityriasis alba (PA) is a skin disorder characterized by finely scaly, hypopigmented patches, typical of childhood, that also represents an atopic dermatitis (AD) minor sign according to Hanifin and Rajka criteria. It may be isolated or associated with AD representing
Meseret Ashenafi et al.
Molecular and cellular biochemistry, 400(1-2), 9-15 (2014-10-31)
Recently, we showed that the fused chorismate-utilizing enzyme from the antibiotic-producing soil bacterium Streptomyces venezuelae is an anthranilate synthase (designated SvAS), not a 2-amino-2-deoxyisochorismate (ADIC) synthase, as was predicted based on its amino acid sequence similarity to the phenazine biosynthetic
Ho-Youn Kim et al.
Plant science : an international journal of experimental plant biology, 231, 30-39 (2015-01-13)
During ripening fruits undergo several physiological and biochemical modifications that influence quality-related properties, such as texture, color, aroma and taste. We studied the differences in ethylene and sugar metabolism between two genetically related Japanese plum cultivars with contrasting ripening behaviors.
W T Regenold et al.
Psychoneuroendocrinology, 25(6), 593-606 (2000-06-07)
This study was undertaken to test the hypothesis that a specific pathophysiological mechanism of diabetic neuropathy, namely increased polyol pathway flux, could be operative in patients with bipolar and unipolar mood disorders. Numerous studies have shown abnormalities of carbohydrate metabolism
Kun Du et al.
Biotechnology progress, 31(1), 42-47 (2014-11-08)
Multiple enzyme mixtures are attractive for the production of many compounds at an industrial level. We report a practical and novel approach for coimmobilization of two enzymes. The system consists of a silica microsphere core coated with two layers of
Edward Sisco et al.
The Analyst, 140(8), 2785-2796 (2015-02-27)
This work highlights the rapid detection of nitrate ester explosives and their sugar alcohol precursors by direct analysis in real time mass spectrometry (DART-MS) using an off-axis geometry. Demonstration of the effect of various parameters, such as ion polarity and
Sharon Wein et al.
Antimicrobial agents and chemotherapy, 58(9), 5519-5527 (2014-07-09)
Bis-thiazolium salts constitute a new class of antihematozoan drugs that inhibit parasite phosphatidylcholine biosynthesis. They specifically accumulate in Plasmodium- and Babesia-infected red blood cells (IRBC). Here, we provide new insight into the choline analogue albitiazolium, which is currently being clinically
Nicolli B de Souza et al.
Malaria journal, 13, 469-469 (2014-12-03)
Given the threat of resistance of human malaria parasites, including to artemisinin derivatives, new agents are needed. Chloroquine (CQ) has been the most widely used anti-malarial, and new analogs (CQAns) presenting alkynes and side chain variations with high antiplasmodial activity
M Tokuda et al.
Connective tissue research, 56(1), 44-49 (2014-11-06)
To examine the responses of mouse odontoblast-lineage cell line (OLC) cultures to xylitol-induced hypertonic stress. OLCs were treated with xylitol, sucrose, sorbitol, mannitol, arabinose and lyxose. Cell viability was evaluated using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium assay. The expression of transient receptor
Raquel dos Santos et al.
Journal of chromatography. A, 1355, 115-124 (2014-06-21)
In this work, phenylboronic acid (PBA) was thoroughly investigated as a synthetic ligand for the purification of an immunoglobulin G (IgG) from a clarified cell supernatant from Chinese Hamster Ovary (CHO) cell cultures. In particular, the study was focused on
G Sundkvist et al.
Diabetic medicine : a journal of the British Diabetic Association, 17(4), 259-268 (2000-05-23)
Sorbitol and myo-inositol levels and morphology of sural nerve were compared with nerve function and clinical neuropathy in men with diabetic, impaired (IGT), and normal glucose tolerance. After neurography of sural nerve and determinations of sensory thresholds for vibration, warm
Fernando Fernández-Bañares et al.
Current gastroenterology reports, 11(5), 368-374 (2009-09-22)
Important dietary carbohydrates such as fructose and sorbitol are incompletely absorbed in the normal small intestine. This malabsorption is sometimes associated with abdominal complaints and diarrhea development, symptoms indistinguishable from those of functional bowel disease. Recently, polymerized forms of fructose
Michele T Jay-Russell et al.
PloS one, 9(11), e113433-e113433 (2014-11-21)
In 2010, Romaine lettuce grown in southern Arizona was implicated in a multi-state outbreak of Escherichia coli O145:H28 infections. This was the first known Shiga toxin-producing E. coli (STEC) outbreak traced to the southwest desert leafy green vegetable production region
Brian A Burt
Journal of the American Dental Association (1939), 137(2), 190-196 (2006-03-09)
The author compared the caries-inhibitory action of sorbitol- and xylitol-sweetened chewing gum and assessed the role of these products in caries prevention. The author reviewed studies including randomized field trials with substantial numbers of participants and observational studies. He did
Arlette Bochud et al.
Biochimica et biophysica acta, 1851(5), 629-640 (2015-02-18)
Five yeast enzymes synthesizing various glycerophospholipids belong to the CDP-alcohol phosphatidyltransferase (CAPT) superfamily. They only share the so-called CAPT motif, which forms the active site of all these enzymes. Bioinformatic tools predict the CAPT motif of phosphatidylinositol synthase Pis1 as
Jianying Huang et al.
Brain : a journal of neurology, 137(Pt 6), 1627-1642 (2014-04-30)
Sodium channel Nav1.9 is expressed in peripheral nociceptive neurons, as well as visceral afferents, and has been shown to act as a threshold channel. Painful peripheral neuropathy represents a significant public health challenge and may involve gain-of-function variants in sodium
Papa Alioune Ndour et al.
The Journal of infectious diseases, 211(2), 290-297 (2014-09-04)
In Plasmodium falciparum-infected patients treated with artemisinins, parasitemia declines through so-called pitting, an innate splenic process that transforms infected red blood cells (iRBCs) into once-infected RBCs (O-iRBCs). We measured pitting in 83 French travelers and 42 Malian children treated for
Yoichi Ishii et al.
Biological & pharmaceutical bulletin, 38(2), 306-316 (2014-12-17)
Cell culture processes that produce therapeutic antibodies with high productivity (titer) and low aggregate content reduce the risk of adverse effects and expense to patients. To elucidate the mechanism of aggregate formation, we compared trastuzumab samples produced from two contrasting
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