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  • The use of sorbitol- and xylitol-sweetened chewing gum in caries control.

The use of sorbitol- and xylitol-sweetened chewing gum in caries control.

Journal of the American Dental Association (1939) (2006-03-09)
Brian A Burt
ABSTRACT

The author compared the caries-inhibitory action of sorbitol- and xylitol-sweetened chewing gum and assessed the role of these products in caries prevention. The author reviewed studies including randomized field trials with substantial numbers of participants and observational studies. He did not review case studies. He found studies through a MEDLINE search and by hand searching. When compared with sugar-sweetened gum, sorbitol-sweetened gum had low cariogenicity [corrected] when it was chewed no more than three times per day. Xylitol-sweetened gum was noncariogenic in all of the protocols tested. Some studies claimed that xylitol-sweetened gum had an anticariogenic effect, though these claims need further study. There also is good evidence that when mothers of infants and young children chew xylitol-sweetened gum, it will block transmission of mutans streptococci from mother to child. The evidence is strong enough to support the regular use of xylitol-sweetened gum as a way to prevent caries, and it can be promoted as a public-health preventive measure. Chewing xylitol-sweetened gum, especially for patients who like chewing gum, can be fitted readily into a regimen that includes frequent fluoride exposure, good oral hygiene and regular dental appointments.

MATERIALS
Product Number
Brand
Product Description

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Xylitol, analytical standard
Sigma-Aldrich
D-Sorbitol, ≥98% (GC), BioXtra
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D-Sorbitol, 99% (GC)
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D-Sorbitol, liquid, tested according to Ph. Eur.
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D-Sorbitol, BioUltra, ≥99.0% (HPLC)
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D-Sorbitol, ≥98% (GC), BioReagent, suitable for cell culture, suitable for plant cell culture
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D-Sorbitol, ≥98% (GC), Molecular Biology
Supelco
Xylitol, Pharmaceutical Secondary Standard; Certified Reference Material
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Xylitol
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Xylitol, ≥99% (GC)
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Sorbitol F solution, 70 wt. % in H2O, Contains mainly D-sorbitol with lesser amounts of other hydrogenated oligosaccharides
USP
Sorbitol, United States Pharmacopeia (USP) Reference Standard
Supelco
Sorbitol, Pharmaceutical Secondary Standard; Certified Reference Material
Sorbitol, European Pharmacopoeia (EP) Reference Standard
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D-Sorbitol, Vetec, reagent grade, 97%
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