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Showing 61-90 of 365 results for "c0625" within Papers
Qian Xie et al.
ACS chemical biology, 10(1), 262-268 (2014-09-24)
Kinases control many aspects of cellular signaling and are therefore therapeutic targets for numerous disease states. Monitoring the conformational changes that drive activation and inactivation of the catalytic kinase core is a challenging experimental problem due to the dynamic nature
Yujing Sun et al.
Molecules (Basel, Switzerland), 18(1), 561-573 (2013-01-08)
The degradation of caffeic acid under ultrasound treatment in a model system was investigated. The type of solvent and temperature were important factors in determining the outcome of the degradation reactions. Liquid height, ultrasonic intensity and duty cycle only affected
Longhai Dai et al.
Plant & cell physiology, 56(6), 1172-1182 (2015-03-12)
Mogrosides, the major bioactive components isolated from the fruits of Siraitia grosvenorii, are a family of cucurbitane-type tetracyclic triterpenoid saponins that are used worldwide as high-potency sweeteners and possess a variety of notable pharmacological activities. Mogrosides are synthesized from 2,3-oxidosqualene
Canan Sevimli-Gur et al.
Molecular biology reports, 46(4), 3691-3699 (2019-04-21)
Detached leaves of Posidonia oceanica and Zostera marina creating nuisance at the shores were extracted by means of supercritical CO2 enriched with a co-solvent, compared with that of soxhlet extraction. The extracts and their active compounds which are phenylpropanoids (chicoric
Hiroko Tani et al.
Bioorganic & medicinal chemistry, 18(1), 151-157 (2009-11-28)
The effects of Brazilian green propolis ethanol extract on Cry j1-induced cys-leukotrienes and histamine release from peripheral leukocytes of patients with allergic rhinitis were investigated. One of the key mechanisms for the anti-allergic properties of the extract was revealed to
Oscar Abel Sánchez-Velázquez et al.
Food & function, 12(16), 7358-7378 (2021-06-29)
Gastrointestinal digestion (GID) is a physiological process that transforms the stability, bioaccessibility and antioxidant activity (AOX) of polyphenols from blackberries (Rubus spp.). This study aimed to investigate the effect of the INFOGEST® GID protocol on the phenolic stability, bioaccessibility and
Wen-Cheng Huang et al.
Food & function, 6(8), 2550-2560 (2015-06-23)
Propionibacterium acnes is a key pathogen involved in acne inflammation. Wild bitter melon (WBM, Momordica charantia L. var. abbreviate Seringe) is consumed as both a vegetable and as folk medicine in Taiwan. We examined the inhibitory activity of the total
Naseer Ali Shah et al.
BioMed research international, 2014, 726241-726241 (2014-07-02)
Jurinea dolomiaea Boiss., family Compositae, is a medicinally important plant of alpine region. Its tuberous roots are used in various ailments in folk medicine. This study was undertaken to estimate total phenolic (TPC) and total flavonoid contents (TFC) and to
Vesna Rastija et al.
European journal of medicinal chemistry, 44(1), 400-408 (2008-04-12)
Quantitative structure activity relationships (QSAR) were obtained describing the antioxidant activity of the main pharmacologically active polyphenols of wine, using molecular properties and descriptors derived from the 2D and 3D representations of molecules. The best models for the prediction of
Janique Vandal et al.
Pharmaceutical biology, 53(6), 800-806 (2015-02-24)
The number of multidrug resistant (MDR) microorganisms is increasing and the antimicrobial resistance expressed by these pathogens is generating a rising global health crisis. In fact, there are only a few antimicrobial agents left that can be used against MDR
Vandana Srivastava et al.
Bioorganic & medicinal chemistry, 15(1), 518-525 (2006-10-13)
Several diverse analogues of Oenostacin, a naturally occurring potent antibacterial phenolic acid derivative, have been synthesized. A small library with more than forty analogues having different aromatic rings and varied side chains has been achieved through solution phase synthesis. Some
María Pilar de Torre et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 129, 110424-110424 (2020-06-22)
Aging-related diseases can be triggered by multiple factors such as oxidative stress. Oxidative stress is an imbalance between free radicals and antioxidants, so today, compounds capable of reducing or neutralizing free radicals are being studied for a therapeutic use. Origanum
Alper Gökbulut et al.
Natural product communications, 8(4), 475-478 (2013-06-07)
Three Inula species, I. viscosa, I. helenium ssp. turcoracemosa and I. montbretiana, collected from different locations of Anatolia were investigated for their antioxidant and antimicrobial potential, and their total phenolic content and phenolic composition. Antioxidant activities of various extracts of
Comparing antioxidative food additives and secondary plant products-use of different assays
Kranl K, et al.
Food Chemistry, 93(1), 171-175 (2005)
Yue Li et al.
Bioorganic & medicinal chemistry, 19(6), 2074-2083 (2011-02-26)
Cyclooxygenase-1/2 (COX-1/2) and 5-lipoxygenase (5-LOX) are enzymes in two different pathways in the inflammatory process. In the present study, a variety of new nimesulide derivatives were synthesized through incorporation of a 5-LOX pharmacophore into nimesulide followed with some structural modifications
M Simunović et al.
Bioorganic & medicinal chemistry, 17(15), 5605-5613 (2009-07-08)
The novel urea primaquine derivatives 3 were prepared by aminolysis of primaquine benzotriazolide 2 with several hydroxyamines and ethylendiamine, while carbamates 4 were synthesized from the same precursor 2 and alcohols. All compounds are fully chemically characterized and evaluated for
L N Cariddi et al.
Environmental toxicology and pharmacology, 39(3), 1008-1018 (2015-04-14)
The present study aimed to investigate the protective effects of luteolin (L), chlorogenic acid (ChlA) and caffeic acid (CafA) against cyto-genotoxic effects caused by OTA. Vero cells and rat lymphocytes were used and viability was measured by neutral red uptake
Hojae Lee et al.
Nature neuroscience, 24(12), 1673-1685 (2021-11-17)
Amyotrophic lateral sclerosis (ALS) is a devastating disorder in which motor neurons degenerate, the causes of which remain unclear. In particular, the basis for selective vulnerability of spinal motor neurons (sMNs) and resistance of ocular motor neurons to degeneration in
Rachel R Schendel et al.
Carbohydrate research, 407, 16-25 (2015-02-24)
In comparison to the annual grain crops dominating current agricultural production, perennial grain species require fewer chemical and energy inputs and improve soil health and erosion control. The possibility for producing sustainable grain harvests from marginal land areas is motivating
Dieter Schemeth et al.
Analytica chimica acta, 885, 199-206 (2015-08-02)
In this study we report the novel polymeric resin poly(N-vinyl imidazole/ethylene glycol dimethacrylate) for the purification and isolation of phenolic acids. The monomer to crosslinker ratio and the porogen composition were optimized for isolating phenolic acids diluted in acetonitrile at
Youji Okada et al.
Journal of food science, 77(11), C1211-C1217 (2012-10-13)
We examined the free radical scavenging activity of Sasa veitchii extract (Hoshi's Striped Bamboo Extract(®), HSBE), well known in folk medicine as an efficient drug and antioxidant in detail. To evaluate the free radical scavenging activity of HSBE, its reactivity
Andrzej L Dawidowicz et al.
Journal of food science and technology, 52(7), 4523-4529 (2015-07-04)
The presented paper shows the influence of temperature increase in the range typically used during antioxidant measurements (15-35 °C) on the estimation of antioxidant properties of phenolic compounds (caffeic acid, ferulic acid, gallic acid, trolox, butylhydroxyanisole, butylhydroxytoluene and 2,6-diisopropylphenol) in associating
Rubén del Barrio-Galán et al.
Journal of the science of food and agriculture, 95(10), 2132-2144 (2014-09-27)
The objective of this work was to study the effect of two Saccharomyces cerevisiae yeast strains with different capabilities of polysaccharide liberation during alcoholic fermentation in addition to subsequent aging on lees with or without oak wood chips as well
Roghieh Hajiboland et al.
Physiology and molecular biology of plants : an international journal of functional plant biology, 24(6), 1103-1115 (2018-11-15)
Effect of silicon (Si) on the response of strawberry (Fragaria × ananassa var. Parus) plants to arbuscular mycorrhizal fungus (AMF) was studied under growth chamber conditions. Plants were grown in perlite irrigated with nutrient solution without (- Si) or with (+ Si) 3 mmol L-1 Si
Eszter Riethmüller et al.
Journal of pharmaceutical and biomedical analysis, 107, 159-167 (2015-01-17)
Corylus maxima Mill. (Betulaceae) leaves have been used in traditional medicine both internally and externally, nevertheless phytochemical exploration of the plant remains incomplete. In this study, the in vitro antioxidant activity and polyphenolic composition of the ethyl acetate and methanolic
Kristina Habschied et al.
Foods (Basel, Switzerland), 9(2) (2020-02-28)
Antioxidative molecules, such as polyphenols can preserve and prolong the freshness of packaged beers. The aim of this work was to assess the content of polyphenolic compounds (by Folin-Ciocalteu and standard European Brewery Convention method) in different types of industrially
N Mihailovic-Stanojevic et al.
Plant foods for human nutrition (Dordrecht, Netherlands), 68(3), 235-240 (2013-07-06)
The low incidence of cardiovascular disease in Mediterranean countries leads to an increased interest of the scientific community for the Mediterranean diet. Our aim was to evaluate total phenol and flavonoid contents, antioxidant capacity, free radical scavenging activity and potential
Kana Arai et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 31(8), 831-835 (2015-08-11)
In order to analyze trigonelline, caffeine, chlorogenic acid, and their related compounds simultaneously, an HPLC method using an InertSustain C18 column and a mobile phase containing octanesulfonate as an ion-pairing reagent under an acidic condition was developed. The optimum mobile
Chun-nian Xia et al.
Bioorganic & medicinal chemistry letters, 18(24), 6553-6557 (2008-10-28)
Forty caffeate analogues were synthesized via a convenient method starting from vanillin with moderate to good yields. The testing of biological activity of these compounds against HIV-1 integrase indicates that four compounds: bornyl caffeate, bornyl 2-nitrocaffeate, 5-nitrocaffeic acid and 5-nitrocaffeic
Vessela Atanasova-Penichon et al.
Molecular plant-microbe interactions : MPMI, 27(10), 1148-1158 (2014-07-12)
Fusarium verticillioides infects maize ears, causing ear rot disease and contamination of grain with fumonisin mycotoxins. This contamination can be reduced by the presence of bioactive compounds in kernels that are able to inhibit fumonisin biosynthesis. To identify such compounds
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