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Showing 1-30 of 168 results for "H4417" within Papers
Kairui Zhang et al.
Biochemical and biophysical research communications, 450(1), 762-766 (2014-06-24)
NSAIDs are often ingested to reduce the pain and improve regeneration of tendon after tendon injury. Although the effects of NSAIDs in tendon healing have been reported, the data and conclusions are not consistent. Recently, tendon-derived stem cells (TDSCs) have
Harini Raghu et al.
Blood, 125(3), 427-437 (2014-10-23)
Rheumatoid arthritis is a chronic inflammatory disease characterized by synovial hyperplasia, inflammatory cell infiltration, irreversible cartilage and bone destruction, and exuberant coagulation system activity within joint tissue. Here, we demonstrate that the coagulation transglutaminase, factor XIII (fXIII), drives arthritis pathogenesis
Jose L Güell et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 30(4), 286-288 (2014-04-08)
To present a case of a late, deep stromal scar in a 22-year-old patient with forme fruste keratoconus who underwent combined corneal cross-linking and photorefractive keratectomy (PRK). Topography-guided corneal cross-linking combined with corneal PRK (without complications) was performed in both
George D Kymionis et al.
American journal of ophthalmology, 158(4), 671-675 (2014-07-19)
To compare the corneal stromal demarcation line depth using anterior segment optical coherence tomography (AS-OCT) after corneal collagen cross-linking (CXL) using 2 different treatment protocols: the standard Dresden protocol (30 minutes with 3 mW/cm(2)) and a modified-accelerated protocol (14 minutes
He Li et al.
Investigative ophthalmology & visual science, 54(7), 4675-4682 (2013-06-15)
Trachoma is a conjunctival scarring disease, which is the leading infectious cause of blindness worldwide. Elimination of blinding trachoma is being held back by the high rate of trichiasis recurrence following surgery. There is currently no treatment available to suppress
Xiaomin He et al.
Journal of nanoscience and nanotechnology, 13(6), 3818-3825 (2013-07-19)
Electrospinning has recently received much attention, showing great potential as a novel scaffold fabrication method for cartilage tissue engineering. In this study, we developed a biodegradable hybrid nanofibrous membrane of collagen and poly(L-lactic acid-co-epsilon-caprolactone) (PLCL, 75:25) by electrospinning for cartilage
Katarina Wolf et al.
The Journal of cell biology, 201(7), 1069-1084 (2013-06-27)
Cell migration through 3D tissue depends on a physicochemical balance between cell deformability and physical tissue constraints. Migration rates are further governed by the capacity to degrade ECM by proteolytic enzymes, particularly matrix metalloproteinases (MMPs), and integrin- and actomyosin-mediated mechanocoupling.
Emily Hams et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(1), 367-372 (2013-12-18)
Disease conditions associated with pulmonary fibrosis are progressive and have a poor long-term prognosis with irreversible changes in airway architecture leading to marked morbidity and mortalities. Using murine models we demonstrate a role for interleukin (IL)-25 in the generation of
Meng Hu et al.
The Journal of pharmacology and experimental therapeutics, 351(1), 87-95 (2014-07-23)
Myofibroblasts are effector cells in fibrotic disorders that synthesize and remodel the extracellular matrix (ECM). This study investigated the role of the Src kinase pathway in myofibroblast activation in vitro and fibrogenesis in vivo. The profibrotic cytokine, transforming growth factor
Akiko Nagaishi et al.
Nihon rinsho. Japanese journal of clinical medicine, 71(5), 876-880 (2013-06-20)
Patients with myasthenia gravis(MG) are divided into three groups: (1) acetylcholine receptor antibody positive MG: 80%, (2) muscle-specific receptor tyrosine kinase (MuSK) antibody positive MG: 5-10%, and (3) double seronegative MG. In 2011, autoantibodies (Abs) against low-density lipoprotein receptor-related protein
Dane K Lund et al.
American journal of physiology. Cell physiology, 307(2), C140-C149 (2014-06-06)
The twenty-five known matrix metalloproteases (MMPs) and their endogenous inhibitors, tissue inhibitors of metalloproteases (TIMPs), mediate cell invasion through the extracellular matrix (ECM). In a comparative three-dimensional assay, we analyzed human and mouse satellite cells' competence to invade an artificial
E Tong et al.
Journal of wound care, 23(7), 355-357 (2014-07-22)
Reconstruction of large abdominal wall defects is a challenging procedure, often contraindicated in critically ill patients, with high incidences of complications. We present a case of a patient with a large abdominal wall defect who had reconstruction with MatriDerm® (an
M K Murphy et al.
Journal of dental research, 92(8), 753-758 (2013-06-21)
The frequency and impact of temporomandibular joint (TMJ) disorders necessitate research in characterizing the joint's function. The 6 discal attachments have not yet been systematically characterized under tension. Understanding their role in joint function may guide our study of TMJ
David Tabibian et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 30(12), 855-857 (2014-12-02)
To report the use of accelerated photoactivated chromophore for keratitis-corneal collagen cross-linking (PACK-CXL) as a first-line treatment in a patient with an atypical fungal keratitis. Case report and literature review. A patient who presented with a painful peripheral corneal infiltrate
David Lu et al.
The Journal of biological chemistry, 288(26), 19040-19049 (2013-05-17)
The establishment of set points for cellular activities is essential in regulating homeostasis. Here, we demonstrate key determinants of the fibrogenic set point of cardiac fibroblasts (CFs) by focusing on the pro-fibrotic activity of ATP, which is released by CFs.
Discussion.
Surgery, 156(4), 908-909 (2014-09-23)
Arthur Hammer et al.
Investigative ophthalmology & visual science, 55(5), 2881-2884 (2014-03-29)
New corneal cross-linking (CXL) devices are capable of using higher UV-A light irradiances than used in original CXL protocols. The Bunsen-Roscoe law states that a photochemical reaction should stay constant if the delivered total energy is kept constant; however, little
Qian Zhang et al.
The Journal of experimental medicine, 211(13), 2549-2566 (2014-11-26)
DOCK8 mutations result in an inherited combined immunodeficiency characterized by increased susceptibility to skin and other infections. We show that when DOCK8-deficient T and NK cells migrate through confined spaces, they develop cell shape and nuclear deformation abnormalities that do
Marjan M Tajrishi et al.
Biochemical and biophysical research communications, 446(4), 1219-1224 (2014-04-01)
Progressive loss of skeletal muscle mass and strength (sarcopenia) is a major clinical problem in the elderly. Recently, proinflammatory cytokine TWEAK and its receptor Fn14 were identified as key mediators of muscle wasting in various catabolic states. However, the role
SuRak Eo et al.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 68(1), 104-112 (2014-12-03)
Fifteen rabbits were used to assess the effect of Lipo-PGE1 on neovascularization. Merocel(®) and Alloderm(®) of the same size were implanted separately under the back skin to act as matrices for vessel growth. Lipo-PGE1 was injected intravenously for 2 weeks
Nwanmegha Young et al.
The Annals of otology, rhinology, and laryngology, 123(11), 765-768 (2014-06-21)
The predictability of laryngeal cancer spread is due in part to connective tissue membranes. These membranes function as barriers to cancer and divide the larynx into subunits. The field of laryngeal conservation surgery is based on these concepts. The quadrangular
Shaun D Mendenhall et al.
Plastic and reconstructive surgery, 135(1), 29e-42e (2014-12-30)
Use of acellular dermal matrix in tissue expander breast reconstruction has become a popular adjunct to the total submuscular technique. The question remains as to which matrix, if any, is ideal for breast reconstruction. A randomized trial was conducted to
Yan Bi et al.
American journal of physiology. Cell physiology, 307(7), C622-C633 (2014-08-01)
Hepatic stellate cells (HSCs) generate matrix, which in turn may also regulate HSCs function during liver fibrosis. We hypothesized that HSCs may endocytose matrix proteins to sense and respond to changes in microenvironment. Primary human HSCs, LX2, or mouse embryonic
Caroline Forsell et al.
The Annals of thoracic surgery, 98(1), 65-71 (2014-06-03)
The prevalence for thoracic aortic aneurysms (TAAs) is significantly increased in patients with a bicuspid aortic valve (BAV) compared with patients who have a normal tricuspid aortic valve (TAV). TAA rupture is a life-threatening event, and biomechanics-based simulations of the
Maurits L van Montfoort et al.
Arteriosclerosis, thrombosis, and vascular biology, 34(8), 1668-1673 (2014-06-21)
Coagulation factor XI is proposed as therapeutic target for anticoagulation. However, it is still unclear whether the antithrombotic properties of factor XI inhibitors influence atherosclerotic disease and atherothrombosis. Our aim is to investigate whether factor XI antisense oligonucleotides could prevent
Visian toric ICL implantation for residual refractive errors after ICRS implantation and corneal collagen cross-linking in keratoconus.
Elias Jarade et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 29(7), 444-444 (2013-07-04)
Mark A Castanares et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(5), 805-811 (2014-04-05)
Genetic reporters provide a noninvasive method to monitor and evaluate a population of cells. The ideal properties of a gene reporter-probe system include biocompatibility, lack of immunogenicity, low background expression or signal, and high sensitivity of detection. The prostate-specific membrane
Sirintip Chaichalotornkul et al.
Biochemical and biophysical research communications, 456(1), 92-97 (2014-12-03)
Secondhand cigarette smoke exposure (SSE) has been linked to carcinogenic, oxidative, and inflammatory reactions. Herein, we investigated whether premature skin aging could be induced by SSE in a rat model, and assessed the cytoplasmic translocation of high mobility group box
Arianna Carolina Rosa et al.
The Journal of pharmacology and experimental therapeutics, 351(2), 308-316 (2014-09-04)
Pulmonary fibrosis, a progressive and lethal lung disease characterized by inflammation and accumulation of extracellular matrix components, is a major therapeutic challenge for which new therapeutic strategies are warranted. Cyclooxygenase (COX) inhibitors have been previously utilized to reduce inflammation. Histamine
High fluence iontophoretic corneal collagen cross-linking: in vivo OCT imaging of riboflavin penetration.
Paolo Vinciguerra et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 29(6), 376-377 (2013-06-07)
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