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Showing 1-30 of 57 results for "L8402" within Papers
Davide Gallo et al.
Experimental biology and medicine (Maywood, N.J.), 239(3), 337-346 (2014-02-06)
Diabetic nephropathy is the leading cause of chronic renal disease and one of the major causes of cardiovascular mortality. Evidence suggests that its progression is due to the chronic hyperglycemia consequent to the production and accumulation of advanced glycation endproducts
Camille S Padlan et al.
RNA (New York, N.Y.), 20(4), 447-461 (2014-02-27)
RNA aptamers are being developed as inhibitors of macromolecular and cellular function, diagnostic tools, and potential therapeutics. Our understanding of the physical nature of this emerging class of nucleic acid-protein complexes is limited; few atomic resolution structures have been reported
Vytautas Gapsys et al.
Biophysical journal, 104(1), 196-207 (2013-01-22)
Analysis of the internal dynamics of a biological molecule requires the successful removal of overall translation and rotation. Particularly for flexible or intrinsically disordered peptides, this is a challenging task due to the absence of a well-defined reference structure that
L Zhang et al.
Poultry science, 93(1), 46-53 (2014-02-27)
This study was conducted to investigate the effects of Clostridium butyricumon growth performance, immune function, and cecal microflora in broiler chickens challenged with Escherichia coli K88. Three hundred sixty 1-d-old broiler chickens were randomly divided into 4 treatments: negative control
Robert D Turner et al.
Nature communications, 4, 1496-1496 (2013-02-21)
Cellular integrity and morphology of most bacteria is maintained by cell wall peptidoglycan, the target of antibiotics essential in modern healthcare. It consists of glycan strands, cross-linked by peptides, whose arrangement determines cell shape, prevents lysis due to turgor pressure
Thomas R M Barends et al.
Nature, 505(7482), 244-247 (2013-11-26)
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which allow data collection from nanometre- to micrometre-sized crystals in a 'diffraction-before-destruction' approach. So far
Guillaume Roussel et al.
Current protocols in protein science, Chapter 28, Unit28-Unit28 (2013-04-03)
Currently, the investigation of protein refolding processes involves several time-consuming stages that require large amounts of protein and costly chemicals. Consequently, there is great interest in developing new approaches to the study of protein renaturation that are more technically and
Dennis J Orton et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 921-922, 75-80 (2013-02-26)
As an alternative to direct UV absorbance measurements, estimation of total protein concentration is typically conducted through colorimetric reagent assays. However, for protein-limited applications, the proportion of the sample sacrificed to the assay becomes increasingly significant. This work demonstrates a
Elspeth F Garman
Science (New York, N.Y.), 343(6175), 1102-1108 (2014-03-08)
The three-dimensional structures of large biomolecules important in the function and mechanistic pathways of all living systems and viruses can be determined by x-ray diffraction from crystals of these molecules and their complexes. This area of crystallography is continually expanding
Anne Derbise et al.
The Journal of infectious diseases, 207(10), 1535-1543 (2013-02-14)
Yersinia pestis (the plague bacillus) and its ancestor, Yersinia pseudotuberculosis (which causes self-limited bowel disease), encode putative homologues of the periplasmic lysozyme inhibitor Ivy and the membrane-bound lysozyme inhibitor MliC. The involvement of both inhibitors in virulence remains subject to
Shangjing Xin et al.
Journal of biomedical nanotechnology, 10(5), 803-810 (2014-04-17)
Layer-by-layer coating technique is effective in modifying the surface of nanofibrous mats, but overmuch film-coating makes the mats less porous to hardly suit the condition for tissue engineering. We developed novel nanofibrous mats layer-by-layer coated by silk fibroin and lysozyme
Mahdieh Mansouri et al.
Molecules (Basel, Switzerland), 18(1), 789-813 (2013-01-25)
The interactions between cyclophosphamide (CYC) and lysozyme (LYZ) in the presence of different cyclodextrins (CDs) were investigated by UV absorption, fluorescence spectroscopy, circular dichroism (CD), and molecular modeling techniques under imitated physiological conditions. The UV absorption results showed the formation
E D N S Abeyrathne et al.
Poultry science, 93(4), 1001-1009 (2014-04-08)
Ovalbumin, ovotransferrin, ovomucin, and lysozyme are a few of the egg white proteins that can be used as functional components. The objective of this study was to develop a simple, sequential separation method for multiple proteins from egg white. Separated
Mariela G Del Giudice et al.
Infection and immunity, 81(3), 956-964 (2013-01-16)
Secretion of proteins in Gram-negative bacteria is a high-energy-consuming process that requires translocation across two membranes and a periplasmic space composed of a mesh-like layer, the peptidoglycan. To achieve this, bacteria have evolved complex secretion systems that cross these barriers
Crystallographic studies of the activity of hen egg-white lysozyme.
C C Blake et al.
Proceedings of the Royal Society of London. Series B, Biological sciences, 167(1009), 378-388 (1967-04-18)
P F Zabrodskiĭ et al.
Eksperimental'naia i klinicheskaia farmakologiia, 75(11), 19-21 (2013-01-18)
It is established in experiments on noninbred rats that the use of imunofan (20 mg/kg daily) and polyoxidonium (150 mg/kg daily) for 7 days on the background of chronic intoxication with organophosphorus agent VX (0.01 LD50, single daily treatment for
Natural Food Antimicrobial Systems (2000)
Meng-xing Wang et al.
Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 48(9), 545-549 (2013-12-10)
To detect the salivary factors related to caries and periodontal disease and to analyze the risk of caries and periodontal disease in children and adolescents with diabetes mellitus. The study comprised 30 children with diabetic mellitus, aged 7-15 years old
Simin Masoudi et al.
Investigative ophthalmology & visual science, 55(2), 767-775 (2014-01-11)
To establish the use of selected reaction monitoring (SRM) mass spectrometry for quantification of tear proteins. Tear samples were collected on multiple occasions (7-10 days) from healthy subjects with contact lens wear (CL = 3) and without contact lens wear
Haining Yu et al.
Zoological science, 30(11), 938-943 (2013-11-10)
Lysozymes are key proteins that play important roles in innate immune defense in many animal phyla by breaking down the bacterial cell-walls. In this study, we report the molecular cloning, sequence analysis and phylogeny of the first caudate amphibian g-lysozyme:
Dev K Ranjit et al.
Journal of bacteriology, 195(11), 2452-2462 (2013-04-02)
Interactions with immune responses or exposure to certain antibiotics can remove the peptidoglycan wall of many Gram-negative bacteria. Though the spheroplasts thus created usually lyse, some may survive by resynthesizing their walls and shapes. Normally, bacterial morphology is generated by
N S Aĭrapetova et al.
Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury, (2)(2), 8-13 (2013-05-31)
The results of this study indicate that the application of gas-air carbonate baths resulted in the reduction of alveolar hypoxia, moderate increase in the patency of central bronchi, marked improvement of pulmonary and systemic cardiohemodynamics, and functional state of cellular
Adam Cryar et al.
Journal of AOAC International, 96(6), 1350-1361 (2014-03-22)
Current routine food allergen quantification methods, which are based on immunochemistry, offer high sensitivity but can suffer from issues of specificity and significant variability of results. MS approaches have been developed, but currently lack metrological traceability. A feasibility study on
Johannes Möller et al.
Physical review letters, 112(2), 028101-028101 (2014-02-04)
We present results from small-angle x-ray scattering data on the effect of high pressure on the phase behavior of dense lysozyme solutions in the liquid-liquid phase separation region, and characterize the underlying intermolecular protein-protein interactions as a function of temperature
Tomoya Takada et al.
Journal of nanoscience and nanotechnology, 14(4), 3216-3220 (2014-04-17)
Effect of sidewall carboxylation on protein adsorption behavior of multi-walled carbon nanotubes (MWCNTs) was studied. Two water-soluble proteins, bovine serum albumin (BSA) and egg white lysozyme (LYS), were employed in this work. Carboxylation of MWCNTs suppressed adsorption of BSA, whereas
Adam Ambroziak et al.
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 36(212), 133-136 (2014-04-12)
Milk proteins are characterized by the highest immune stimulative potency from among all the proteins present in human diet. Whey proteins and numerous growth factors that regulate insulin secretion, differentiation of intestine epithelium cells, and also tissue restoration, are priceless
Bum-Yeol Hwang et al.
Journal of nanoscience and nanotechnology, 13(3), 2313-2319 (2013-06-13)
For the functional bacterial surface display of active enzyme of multimeric form, which is generally impossible due to molecular assembly of the monomer subunit subsequent to the secretion of displayed target protein outside the cell, a new surface display system
Yashwanth Ashok et al.
Methods in enzymology, 520, 175-198 (2013-01-22)
G-protein-coupled receptors (GPCRs) represent a major class of receptors through which a number of signals ranging from photons to large glycoprotein hormones are recognized. Human genome encodes about 800 GPCRs, yet very little structural information is available on this class
Amy R Wyatt et al.
FEBS letters, 587(5), 398-403 (2013-01-29)
α(2)-Macroglobulin (α(2)M) is an extracellular chaperone that inhibits amorphous and fibrillar protein aggregation. The reaction of α(2)M with proteases results in an 'activated' conformation, where the proteases become covalently-linked within the interior of a cage-like structure formed by α(2)M. This
Md Suhail Alam et al.
The Journal of biological chemistry, 289(12), 8051-8066 (2014-02-04)
Early diagnosis of neurological disorders would greatly improve their management and treatment. A major hurdle is that inflammatory products of cerebral disease are not easily detected in blood. Inflammation in multiple organs and heterogeneity in disease present additional challenges in
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