CN
Search Within
M0880
Applied Filters:
Keyword:'M0880'
Showing 1-30 of 141 results for "M0880" within Papers
Yuan-Ling Chen et al.
Journal of integrative plant biology, 55(2), 122-130 (2012-11-07)
Plant mutants are important bio-resources for crop breeding and gene functional studies. Conventional methods for generating mutant libraries by mutagenesis of seeds with physical or chemical agents are of low efficiency. Here, we developed a highly-efficient ethyl methanesulfonate (EMS) mutagenesis
Benjamin Hartwig et al.
Plant physiology, 160(2), 591-600 (2012-07-28)
Mapping-by-sequencing (or SHOREmapping) has revitalized the powerful concept of forward genetic screens in plants. However, as in conventional genetic mapping approaches, mapping-by-sequencing requires phenotyping of mapping populations established from crosses between two diverged accessions. In addition to the segregation of
Marlies De Boeck et al.
Mutation research. Genetic toxicology and environmental mutagenesis, 786-788, 151-157 (2015-07-28)
As part of the Japanese Center for the Validation of Alternative Methods (JaCVAM)-initiated international validation study of in vivo rat alkaline comet assay (comet assay), p-phenylenediamine dihydrochloride (PPD), o-phenylphenol sodium salt (OPP), and 2,4-diaminotoluene (2,4-DAT), were analyzed in this laboratory
B K Mable et al.
Genetical research, 77(1), 9-26 (2001-03-31)
The yeast, Saccharomyces cerevisiae, was used as a model to investigate theories of ploidy evolution. Mutagenesis experiments using the alkylating agent EMS (ethane methyl sulphonate) were conducted to assess the relative importance that masking of deleterious mutations has on response
Arabidopsis EDM2 promotes IBM1 distal polyadenylation and regulates genome DNA methylation patterns.
Mingguang Lei et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(1), 527-532 (2013-11-20)
DNA methylation is important for the silencing of transposons and other repetitive elements in many higher eukaryotes. However, plant and mammalian genomes have evolved to contain repetitive elements near or inside their genes. How these genes are kept from being
Xingkui Tao et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(12), 1731-1733 (2012-09-25)
To determine the optimal concentration and processing time of EMS mutation for suspension cells from Pinellia ternata. Under four EMS concentration gradients (0.1% , 0.2%, 0.4%, 0.6%) and three processing time gradients (0.5, 1.0, 2.0 h), the suspension cells of
Yu-Long Gao et al.
Journal of integrative plant biology, 62(2), 165-180 (2019-01-31)
Targeting-induced local lesions in genomes (TILLING) is a powerful reverse-genetics tool that enables high-throughput screening of genomic variations in plants. Although TILLING has been developed for many diploid plants, the technology has been used in very few polyploid species due
A I Doseff et al.
Genetics, 141(3), 857-871 (1995-11-01)
Saccharomyces cerevisiae mutations that cause a requirement for SSD1-v for viability were isolated, yielding one new gene, LAS1, and three previously identified genes, SIT4, BCK1/SLK1, and SMP3. Three of these genes, LAS1, SIT4, and BCK1/SLK1, encode proteins that have roles
Joanna Jankowicz-Cieslak et al.
Plant biotechnology journal, 10(9), 1056-1066 (2012-08-30)
Mutation discovery technologies have enabled the development of reverse genetics for many plant species and allowed sophisticated evaluation of the consequences of mutagenesis. Such methods are relatively straightforward for seed-propagated plants. To develop a platform suitable for vegetatively propagated species
A Rapid and Precise Mutation-Activated Fluorescence Reporter for Analyzing Acute Mutagenesis Frequency
Birnbaum MD, et al.
Cell Chemical Biology (2018)
Quan Hong Tran et al.
Genes, 11(3) (2020-03-12)
Induced point mutations are important genetic resources for their ability to create hypo- and hypermorphic alleles that are useful for understanding gene functions and breeding. However, such mutant populations have only been developed for a few temperate maize varieties, mainly
Jia Zhenchao et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 75, 50-57 (2014-12-03)
Vegetable carbon has been used as food additive in EU (E153) and China for many years; however, no experimental data have been available on its dietary safety. This study was designed to evaluate the subchronic toxicity and genotoxicity of bamboo
Tendekai Mahlanza et al.
Plant cell reports, 32(2), 249-262 (2012-10-24)
KEY MESSAGE : A combination of in vitro culture and mutagenesis using ethyl methanesulfonate (EMS) followed by culture filtrate-mediated selection produced variant sugarcane plants tolerant and resistant to Fusarium sacchari. Eldana saccharina is a destructive pest of the sugarcane crop
Sarah E Hill et al.
Developmental cell, 49(2), 251-266 (2019-03-19)
In neurons, defects in autophagosome clearance have been associated with neurodegenerative disease. Yet, the mechanisms that coordinate trafficking and clearance of synaptic autophagosomes are poorly understood. Here, we use genetic screens and in vivo imaging in single neurons of C. elegans to
C Ma et al.
Genetics, 142(4), 1199-1213 (1996-04-01)
The glass gene encodes a zinc finger, DNA-binding protein that is required for photoreceptor cell development in Drosophila melanogaster. In the developing compound eye, glass function is regulated at two points: (1) the protein is expressed in all cells' nuclei
Catherine Charles et al.
Food chemistry, 135(4), 2974-2981 (2012-09-18)
The complexity of DNA repair mechanisms infers that xenobiotics, derived from food and medicinal plants, may interfere in the process, activating or inhibiting repair. Different flavonoids were investigated, at the highest non-toxic concentration, for their capacity to modulate DNA repair
Elena De Gianni et al.
Toxins, 7(2), 535-552 (2015-02-14)
One important strategy to develop effective anticancer agents is based on natural products. Many active phytochemicals are in human clinical trials and have been used for a long time, alone and in association with conventional anticancer drugs, for the treatment
C W Op het Veld et al.
Mutagenesis, 12(6), 417-424 (1997-12-31)
The role of the nucleotide excision repair (NER) pathway in removal of DNA ethylation damage was investigated by means of hprt mutational spectra analysis in the NER-deficient Chinese hamster ovary cell line UV5, which lacks ERCC2/XPD, and in its parental
Zhen Zhang et al.
Plant physiology, 182(1), 167-184 (2019-08-06)
Histone deacetylase (HDAC) proteins participate in diverse and tissue-specific developmental processes by forming various corepressor complexes with different regulatory subunits. An important HDAC machinery hub, the Histone Deacetylase Complex1 (HDC1) protein, participates in multiple protein-protein interactions and regulates organ size
Yoshifumi Uno et al.
Mutation research. Genetic toxicology and environmental mutagenesis, 786-788, 45-76 (2015-07-28)
The in vivo rodent alkaline comet assay (comet assay) is used internationally to investigate the in vivo genotoxic potential of test chemicals. This assay, however, has not previously been formally validated. The Japanese Center for the Validation of Alternative Methods
Denis Tagu et al.
G3 (Bethesda, Md.), 4(4), 657-667 (2014-02-18)
In aphids, clonal individuals can show distinct morphologic traits in response to environmental cues. Such phenotypic plasticity cannot be studied with classical genetic model organisms such as Caenorhabditis elegans or Drosophila melanogaster. The genetic basis of this biological process remain
Xuejiao Cheng et al.
The Plant cell, 32(4), 923-934 (2020-02-16)
Six subspecies of hexaploid wheat (Triticumaestivum) have been identified, but the origin of Indian dwarf wheat (Triticum sphaerococcum), the only subspecies with round grains, is currently unknown. Here, we isolated the grain-shape gene Tasg-D1 in Tsphaerococcum via positional cloning. Tasg-D1
Kamel El Omari et al.
Nature communications, 10(1), 846-846 (2019-02-21)
Lipid membrane fusion is an essential function in many biological processes. Detailed mechanisms of membrane fusion and the protein structures involved have been mainly studied in eukaryotic systems, whereas very little is known about membrane fusion in prokaryotes. Haloarchaeal pleomorphic
Yang Dong et al.
Current biology : CB, 30(19), 3880-3888 (2020-08-17)
Morphological variation is the basis of natural diversity and adaptation. For example, angiosperms (flowering plants) evolved during the Cretaceous period more than 100 mya and quickly colonized terrestrial habitats [1]. A major reason for their astonishing success was the formation
William C Gunther et al.
Environmental and molecular mutagenesis, 55(6), 492-499 (2014-03-07)
Ethyl methanesulfonate (EMS) was evaluated as part of the validation effort for the rat Pig-a mutation assay and compared with other well-established in vivo genotoxicity endpoints. Male Sprague-Dawley (SD) rats were given a daily dose of 0, 6.25, 12.5, 25
V Mohan M Achary et al.
Mutation research, 751(2), 130-138 (2013-01-15)
Calcium is an important second messenger in signal transduction pathways. The role of Ca(2+) signalling in Al-induced DNA damage, cell death, and adaptive response to genotoxic stress caused by ethyl methanesulfonate (EMS) or methylmercuric chloride (MMCl) in the root cells
Jie Liu et al.
Cell host & microbe, 28(3), 402-410 (2020-06-17)
Bacteria and their toxins are associated with significant human morbidity and mortality. While a few bacterial toxins are well characterized, the mechanism of action for most toxins has not been elucidated, thereby limiting therapeutic advances. One such example is the
Ratan Chopra et al.
The Plant journal : for cell and molecular biology, 96(6), 1093-1105 (2018-11-06)
Thlaspi arvense (pennycress) has the potential for domestication as a new oilseed crop. Information from an extensive body of research on the related plant species Arabidopsis can be used to greatly speed this process. Genome-scale comparisons in this paper documented
Kanive Parashiva Guruprasad et al.
BMC complementary and alternative medicine, 12, 113-113 (2012-08-03)
Ayurveda, the traditional Indian system of medicine has given great emphasis to the promotion of health. Rasayana is one of the eight branches of Ayurveda which refers to rejuvenant therapy. It has been reported that rasayanas have immuno-modulatory, antioxidant and
Xiaojing Yang et al.
Journal of chromatography. A, 1379, 16-23 (2015-01-13)
Matrix interference, which can lead to false positive/negative results, contamination of injector or separation column, incompatibility between sample solution and the selected analytical instrument, and response inhibition or even quenching, is commonly suffered for the analysis of trace level toxic
Page 1 of 5