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Showing 1-30 of 99 results for "V3501" within Papers
Zhen Hui Lim et al.
The journal of physical chemistry. B, 117(8), 2396-2402 (2013-02-13)
When the quinone, vitamin K1 (VK1), is electrochemically reduced in aqueous-acetonitrile solutions (CH3CN with 7.22 M H2O), it undergoes a two-electron reduction to form the dianion that is hydrogen-bonded with water [VK1(H2O)y(2–)]. EPR and voltammetry experiments have shown that the
L G Israels et al.
Seminars in perinatology, 21(1), 90-96 (1997-02-01)
Vitamin K in the fetus and newborn is maintained at levels less than that necessary to achieve full gamma-carboxylation of the K-dependent proteins, including those required for hemostasis. As the infant matures and even into adulthood, there is no significant
Conall M O'Seaghdha et al.
American journal of nephrology, 36(1), 68-77 (2012-06-23)
Cardiovascular risk factors are associated with the development of chronic kidney disease (CKD), and CKD and vascular disease are etiologically linked. Evidence suggests deficiencies of vitamins D and K may adversely affect the cardiovascular system, but data from longitudinal studies
Bacteroides disiens sp. nov. and Bacteroides bivius sp. nov. from human clinical infections
Holdeman L V and Johnson J L
International Journal of Systematic and Evolutionary Microbiology (1977)
M Kyla Shea et al.
The American journal of clinical nutrition, 98(1), 197-208 (2013-05-31)
Animal studies have shown that vitamin K treatment reduced vascular calcification, but human data are limited. We determined the association between vitamin K status and coronary artery calcium (CAC) progression in the Multi-Ethnic Study of Atherosclerosis by using a case-cohort
Emeline Laborel-Préneron et al.
PloS one, 10(10), e0141067-e0141067 (2015-10-29)
Interactions between the immune system and skin bacteria are of major importance in the pathophysiology of atopic dermatitis (AD), yet our understanding of them is limited. From a cohort of very young AD children (1 to 3 years old), sensitized
Núria Ibarrola-Jurado et al.
The American journal of clinical nutrition, 96(5), 1113-1118 (2012-10-05)
Limited evidence from human and animal studies has suggested that vitamin K has a potentially beneficial role in glucose metabolism and insulin resistance. We analyzed the cross-sectional and longitudinal associations between dietary phylloquinone intake and type 2 diabetes in elderly
D Bates et al.
Pharmacotherapy, 20(10), 1208-1215 (2000-10-18)
We cared for a patient who ingested an unknown amount of acetaminophen with zopiclone and warfarin. The only liver function test that was abnormal was an increased international normalized ratio (INR), which remained elevated despite treatment with subcutaneous phytonadione and
P M Loughnan et al.
Journal of paediatrics and child health, 32(3), 251-254 (1996-06-01)
To propose a hypothesis that the long duration of effect of intramuscular (i.m.) vitamin K1 in preventing late onset haemorrhagic disease results from a depot effect after i.m. injection. Review of scientific literature relating to the pharmacology of vitamin K
Interaction between vitamin K1 and fat absorption.
Nutrition reviews, 34(10), 314-315 (1976-10-01)
Edward P A Gebuis et al.
Haematologica, 96(4), 583-589 (2011-01-05)
Poor anticoagulant stability in patients using vitamin K antagonists is a risk factor for both bleeding and thrombosis. In previous studies supplementation with low dose vitamin K(1) was shown to improve the stability of anticoagulant control. We set up a
Gary Hastings
Biochimica et biophysica acta, 1847(1), 55-68 (2014-08-03)
Fourier transform infrared difference spectroscopy (FTIR DS) has been widely used to study the structural details of electron transfer cofactors (and their binding sites) in many types of photosynthetic protein complexes. This review focuses in particular on work that has
Gabriel S Krigsfeld et al.
International journal of radiation biology, 89(10), 823-831 (2013-05-09)
To determine the mechanism of proton radiation- induced coagulopathy. Ferrets were exposed to either solar particle event (SPE)-like proton radiation at a predetermined dose rate of 0.5 Gray (Gy) per hour (h) for a total dose of 0 or 1
Phylloquinone (vitamin K1): occurrence, biosynthesis and functions
Basset J G, et al.
Mini-Reviews in Medicinal Chemistry (2017)
Shengzhi Xie et al.
Oncotarget, 6(11), 9206-9219 (2015-04-01)
Mer is a receptor tyrosine kinase (RTK) with oncogenic properties that is often overexpressed or activated in various malignancies. Using both immunohistochemistry and microarray analyses, we demonstrated that Mer was overexpressed in both tumoral and stromal compartments of about 70%
Sherry M Farley et al.
Molecular nutrition & food research, 56(6), 912-922 (2012-06-19)
The mechanism for increased bleeding and decreased vitamin K status accompanying vitamin E supplementation is unknown. We hypothesized that elevated hepatic α-tocopherol (α-T) concentrations may stimulate vitamin K metabolism and excretion. Furthermore, α-T may interfere with the side chain removal
Martí Juanola-Falgarona et al.
The Journal of nutrition, 144(5), 743-750 (2014-03-22)
Vitamin K has been related to cardiovascular disease and cancer risk. However, data on total mortality are scarce. The aim of the present study was to assess the association between the dietary intake of different types of vitamin K and
Ji-Hoi Moon et al.
BMC microbiology, 14, 218-218 (2014-08-26)
Polyphosphate (polyP) has bactericidal activity against a gram-negative periodontopathogen Porphyromonas gingivalis, a black-pigmented gram-negative anaerobic rod. However, current knowledge about the mode of action of polyP against P. gingivalis is incomplete. To elucidate the mechanisms of antibacterial action of polyP
M Kyla Shea et al.
Advances in nutrition (Bethesda, Md.), 3(2), 158-165 (2012-04-21)
Vascular calcification occurs when calcium accumulates in the intima (associated with atherosclerosis) and/or media layers of the vessel wall. Coronary artery calcification (CAC) reflects the calcium burden within the intima and media of the coronary arteries. In population-based studies, CAC
S Lembo et al.
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 147(2), 203-205 (2012-04-07)
Vitamin K1 (phytomenadione or phytonadione) is a fat soluble vitamin used to treat certain coagulation disorders. Intra muscular injection of vitamin K1 can occasionally be complicated by different types of skin reactions: erythematous plaques, urticarial rashes or scleroderma-like lesions at
Sam Mula et al.
The journal of physical chemistry. B, 116(48), 14008-14016 (2012-11-10)
The phylloquinone acceptor PhQ(A) in photosystem I binds to the protein through a single H-bond to the backbone nitrogen of PsaA-L722. Here, we investigate the effect of this H-bond on the electron transfer (ET) kinetics by substituting threonine for PsaA-L722.
A Moreau-Cabarrot et al.
Annales de dermatologie et de venereologie, 123(3), 177-179 (1996-01-01)
Skin reactions after vitamin K injections are uncommon and only seen with vitamin K1 (phytomenadione). Possible association with liver disease is debated. The pathophysiological mechanism would be related to hypersensitivity to phytomenadione. Two new cases of hypersensitivity reactions at the
Eibhlís M O'Connor et al.
The British journal of nutrition, 112(7), 1163-1174 (2014-09-03)
Although epidemiological findings support a role for vitamin K status in the improvement of bone indices in adult patients with Crohn's disease (CD), this needs to be confirmed in double-blind, randomised controlled trials (RCT) with phylloquinone (vitamin K1). By conducting
C C Harrell et al.
The Annals of pharmacotherapy, 29(12), 1228-1232 (1995-12-01)
To report 6 patients taking oral vitamin K1 (phytonadione) to reduce warfarin's activity. Six patient cases are summarized in which oral vitamin K1 was used to reduce the international normalized ratio (INR) in patients at risk of bleeding. The use
Paul Clarke et al.
Nutrients, 7(10), 8308-8320 (2015-10-02)
All newborns require phylloquinone after birth to prevent vitamin K deficiency bleeding. Babies born prematurely may be at particular risk of deficiency without adequate supplementation during infancy. The main sources of phylloquinone in preterm babies during the neonatal period are
A A Toropov et al.
European journal of medicinal chemistry, 43(4), 714-740 (2007-07-17)
Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and organic compounds of different classes by optimal descriptors. Statistical characteristics of the best model (vitamins) are the
Hrisi Bahar Tokman et al.
Clinical laboratory, 60(11), 1879-1886 (2015-02-05)
Anaerobic bacteria play an important role in eye infections; however, there is limited epidemiologic data based on the the role of these bacteria in the etiology of keratitis and endophthalmitis. The aim of this re- search is to determine the
Fernanda Luna da Silva et al.
Neurochemistry international, 62(1), 103-112 (2012-10-16)
In the last decades, a series of compounds, including quinones and polyphenols, has been described as having anti-fibrillogenic action on α-synuclein (α-syn) whose aggregation is associated to the pathogenesis of Parkinson's disease (PD). Most of these molecules act as promiscuous
Chiara Martano et al.
Journal of chromatography. A, 1412, 59-66 (2015-08-19)
The analysis of lipid molecules in living organism is an important step in deciphering metabolic pathways. Recently, the zebrafish has been adopted as a valuable animal model system to perform in vivo metabolomics studies, however limited methodologies and protocols are
C Rodriguez et al.
Veterinary microbiology, 172(1-2), 309-317 (2014-06-05)
Clostridium difficile has been identified as a significant agent of diarrhoea and enterocolitis in both foals and adult horses. Hospitalization, antibiotic therapy or changes in diet may contribute to the development of C. difficile infection. Horses admitted to a care
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