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Showing 1-30 of 145 results for "V5265" within Papers
Ksenija Radic Shechter et al.
Molecular systems biology, 17(10), e10141-e10141 (2021-10-26)
Tumor relapse from treatment-resistant cells (minimal residual disease, MRD) underlies most breast cancer-related deaths. Yet, the molecular characteristics defining their malignancy have largely remained elusive. Here, we integrated multi-omics data from a tractable organoid system with a metabolic modeling approach
Nianzhu Zhang et al.
Oncotarget, 7(38), 61587-61600 (2016-08-25)
Septins are a novel class of GTP-binding cytoskeletal proteins evolutionarily conserved from yeast to mammals and have now been found to play a contributing role in a broad range of tumor types. However, their functional importance in breast cancer remains
Salvatore Benfatto et al.
Molecular cancer, 20(1), 111-111 (2021-08-30)
Synthetic lethality describes a genetic interaction between two perturbations, leading to cell death, whereas neither event alone has a significant effect on cell viability. This concept can be exploited to specifically target tumor cells. CRISPR viability screens have been widely
Pranabananda Dutta et al.
Cancers, 12(5) (2020-05-28)
PolyADP ribosylation (PARylation) by PARP1 is a significant post-translational modification affecting protein function in various cancers. However, PARP1 mediated cellular processes in the context of breast cancer are not fully understood. To identify potential targets of PARP1, we carried out
A Blanco-Flores et al.
Environmental technology, 35(9-12), 1508-1519 (2014-04-08)
Textural, structural and morphological characteristics of the vitreous tuff were determined by means of several physicochemical techniques. The nitrogen adsorption isotherm at 77 K was fitted with the Brunnauer-Emmet-Teller model and together with the results of the average pore distribution
Daile Meek C Salvador-Membreve et al.
Experimental parasitology, 147, 33-40 (2014-10-14)
Trichomonas vaginalis, the causative agent of trichomoniasis is generally known to inhabit the genitourinary tract. However, several case reports with supporting molecular and immunological identifications have documented its occurrence in the respiratory tract of neonates and adults. In addition, the
Carole Henry et al.
Cell host & microbe, 25(3), 357-366 (2019-02-24)
Influenza is a leading cause of death in the elderly, and the vaccine protects only a fraction of this population. A key aspect of antibody-mediated anti-influenza virus immunity is adaptation to antigenically distinct epitopes on emerging strains. We examined factors
Gentian Violet: a 19th century drug re-emerges in the 21st century
Alexander M. Maley, Jack L. Arbiser
Experimental Dermatology, 22(12) (2013)
Haruhiro Inoue et al.
Nihon rinsho. Japanese journal of clinical medicine, 66(5), 1023-1027 (2008-05-10)
NBI magnifying imaging with crystal violet (CV-NBI magnifying imaging) makes recognition of micro-vascular pattern and grandular structure in the gastric mucosa better. NBI image emphasizes micro-vascular structure in mucosal surface. Magnification endoscopy with crystal violet staining delineates surface grandular structure
Fengfei Zhou et al.
Ecotoxicology and environmental safety, 105, 1-6 (2014-05-02)
Burkholderia vietnamiensis C09V (B.V. C09V) was used to remove both crystal violet (CV) and Cu(II) because dye effluents often contain dyes and metal ions. Inhibiting the strain׳s growth through the biosorption of Cu(II) on B.V. C09V and promoting its growth
CDK4/6 or MAPK blockade enhances efficacy of EGFR inhibition in oesophageal squamous cell carcinoma.
Jin Zhou et al.
Nature communications, 8, 13897-13897 (2017-01-07)
Oesophageal squamous cell carcinoma is a deadly disease where systemic therapy has relied upon empiric chemotherapy despite the presence of genomic alterations pointing to candidate therapeutic targets, including recurrent amplification of the gene encoding receptor tyrosine kinase epidermal growth factor
Li Qi et al.
International journal of molecular medicine, 38(6), 1734-1742 (2016-10-18)
Prostate carcinoma is a devastating disease which is characterized by insidious early symptoms, rapid progression and a poor prognosis. Tripartite motif-containing protein 16 (TRIM16) was identified as an estrogen- and antiestrogen-regulated gene in epithelial cells stably expressing estrogen receptors. The protein
Hansjörg Hufnagel et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 17(8), 1411-1417 (2009-06-18)
The understanding of internalization pathways of lipo- or polyplexes is crucial for engineering successful reagents for nonviral gene transfection. A known inhibitor of fluid phase endocytosis (FPE), rottlerin, was used to quantify the contribution of this pathway by flow cytometric
Karen J Farid et al.
Geriatric nursing (New York, N.Y.), 32(2), 85-95 (2011-02-18)
To review the use of gentian violet 1% (GV) in a long-term care facility for the treatment of small, open wounds and extremity eschars of all sizes and thickness. The records of all the patients receiving topical GV therapy over
Vijay Pratap Singh et al.
Developmental cell, 54(3), 333-347 (2020-08-18)
Cohesin is an evolutionarily conserved chromosome-associated protein complex essential for chromosome segregation, gene expression, and repair of DNA damage. Mutations that affect this complex cause the human developmental disorder Cornelia de Lange syndrome (CdLS), thought to arise from defective embryonic
Laura Rae et al.
Science & justice : journal of the Forensic Science Society, 53(3), 321-327 (2013-08-14)
A number of studies have reported the successful enhancement of latent fingermarks on fruit and vegetables. A study was set up to identify the most effective technique for the enhancement of fingermarks in blood on various fruit and vegetables. The
Counterion-dye staining method for DNA in agarose gels using crystal violet and methyl orange
Yang, et al.
Electrophoresis, 22(5) (2001)
Nuno Basílio et al.
The Journal of organic chemistry, 78(18), 9113-9119 (2013-08-22)
p-Sulfonatocalix[4]arene (SC4) interacts with the aromatic dye crystal violet (CV) to form complexes with stoichiometries ranging from SC4:CV = 1:1 up to 1:5 both in solution and in the gas phase. While the 1:1 complex is of the inclusion type
Jie Xie et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 913-914, 123-128 (2013-01-05)
A high performance liquid chromatography method with visible detection (HPLC-VIS) for the determination of malachite green (MG), crystal violet (CV), leucomalachite green (LMG), and leucocrystal violet (LCV) in fish has been developed after clean-up through an immunoaffinity column (IAC). Residues
Eunsu Yoo et al.
BMC cancer, 20(1), 881-881 (2020-09-16)
A. oxyphylla extract is known to possess a wide range of pharmacological activites. However, the molecular mechanism of A. oxyphylla and its bioactive compound nootkatone in colorectal cancer is unknown. Our study aims to examine the role of A. oxyphylla
Studies on adsorption of crystal violet dye from aqueous solution onto coniferous pinus bark powder (CPBP)
Ahmad R.
Journal of Hazardous Materials, 171, 767-773 (2009)
Rong Guo et al.
Methods (San Diego, Calif.), 48(1), 72-79 (2009-02-28)
The use of co-immunoprecipitation (co-IP) to purify multi-protein complexes has contributed greatly to our understanding of the DNA damage response network associated with Fanconi anemia (FA), Bloom syndrome (BS) and breast cancer. Four new FA genes and two new protein
Taishi Onodera et al.
Immunity, 54(10), 2385-2398 (2021-09-12)
Potent neutralizing SARS-CoV-2 antibodies often target the spike protein receptor-binding site (RBS), but the variability of RBS epitopes hampers broad neutralization of multiple sarbecoviruses and drifted viruses. Here, using humanized mice, we identified an RBS antibody with a germline VH
N Zhang et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 67(2), 418-423 (2012-11-22)
This paper studies the effect of photosensitizer (acetone, H(2)O(2), surfactant and pigment) on photodegradation of diclofenac (DCF) under simulated sunlight. The results demonstrate that degradation pathways proceed via pseudo first-order kinetics in all cases. The photodegradation rate was found to
Kisoo Pahk et al.
International journal of molecular sciences, 21(1) (2019-12-28)
Interactions between CD147 and cyclophilin A (CypA) promote plaque rupture that causes atherosclerosis-related cardiovascular events, such as myocardial infarction and stroke. Here, we investigated whether SP-8356 ((1S,5R)-4-(3,4-dihydroxy-5-methoxystyryl)-6,6-dimethylbicyclo[3.1.1]hept-3-en-2-one), a novel drug, can exert therapeutic effects against plaque progression and instability through
Se-Hyun Oh et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(6), 7301-7314 (2019-03-13)
Hypercholesterolemia is reported to increase reactive oxygen species (ROS) and to promote breast cancer progression. ROS play an important role in tumor biology, and xanthine oxidase (XO) is an enzyme that generates ROS. The effects of febuxostat (FBX), an XO
Ann-Kathrin Eichelmann et al.
International journal of molecular sciences, 22(11) (2021-06-03)
TP53 gene mutations occur in 70% of oesophageal adenocarcinomas (OACs). Given the central role of p53 in controlling cellular response to therapy we investigated the role of mutant (mut-) p53 and SLC7A11 in a CRISPR-mediated JH-EsoAd1 TP53 knockout model. Response
Characterization of potent and selective iodonium-class inhibitors of NADPH oxidases
Lu J, et al.
Biochemical Pharmacology, 43, 25-38 (2017)
Youngjae Ryu et al.
International journal of molecular sciences, 22(3) (2021-02-03)
Polycystic ovarian syndrome (PCOS) is a common reproductive endocrine disorder in reproductive-age women. Due to its various pathophysiological properties and clinical heterophenotypes, the mechanism of PCOS pathogenesis is still unclear. Several animal models have been used to study PCOS and
David Brunn et al.
Cancers, 13(2) (2021-01-13)
Transcription factors can serve as links between tumor microenvironment signaling and oncogenesis. Interferon regulatory factor 9 (IRF9) is recruited and expressed upon interferon stimulation and is dependent on cofactors that exert in tumor-suppressing or oncogenic functions via the JAK-STAT pathway.
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