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Showing 1-30 of 145 results for "V5265" within Papers
Kamesh R Babu et al.
Scientific reports, 9(1), 1518-1518 (2019-02-08)
Transferrin receptor 1 (TFR1) is a transmembrane glycoprotein that allows for transferrin-bound iron uptake in mammalian cells. It is overexpressed in various cancers to satisfy the high iron demand of fast proliferating cells. Here we show that in hepatocellular carcinoma
Kevin R Bewley et al.
Nature protocols, 16(6), 3114-3140 (2021-04-25)
Virus neutralization assays measure neutralizing antibodies in serum and plasma, and the plaque reduction neutralization test (PRNT) is considered the gold standard for measuring levels of these antibodies for many viral diseases. We have developed procedures for the standard PRNT
L V Lagun et al.
Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (3)(3), 18-23 (2013-09-05)
Study the intensity of formation of microbial biofilms by Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus strains isolated during various forms of pyelonephritis. 150 clinical isolates of microorganisms isolated from urine ofpatientswith acute and chronic pyelonephritiswere included into the
Haineng Xu et al.
Cell reports. Medicine, 2(9), 100394-100394 (2021-10-09)
CCNE1-amplified ovarian cancers (OVCAs) and endometrial cancers (EMCAs) are associated with platinum resistance and poor survival, representing a clinically unmet need. We hypothesized that dysregulated cell-cycle progression promoted by CCNE1 overexpression would lead to increased sensitivity to low-dose WEE1 inhibition
Dong-Keon Kim et al.
Cancers, 12(9) (2020-09-17)
Octamer-binding transcription factor 4 (Oct4) plays an important role in maintaining pluripotency in embryonic stem cells and is closely related to the malignancies of various cancers. Although posttranslational modifications of Oct4 have been widely studied, most of these have not
Histological and histochemical methods: Theory and practice (5th ed.)
JA Kiernan
Histological and Histochemical Methods: Theory and Practice (2015)
Metabolism and mode of action of gentian violet.
S N Moreno
Memorias do Instituto Oswaldo Cruz, 83 Suppl 1, 308-320 (1988-11-01)
Ann-Kathrin Eichelmann et al.
International journal of molecular sciences, 22(11) (2021-06-03)
TP53 gene mutations occur in 70% of oesophageal adenocarcinomas (OACs). Given the central role of p53 in controlling cellular response to therapy we investigated the role of mutant (mut-) p53 and SLC7A11 in a CRISPR-mediated JH-EsoAd1 TP53 knockout model. Response
Alan M O'Neill et al.
eLife, 10 (2021-10-20)
Methicillin-resistant Staphylococcus pseudintermedius (MRSP) is an important emerging zoonotic pathogen that causes severe skin infections. To combat infections from drug-resistant bacteria, the transplantation of commensal antimicrobial bacteria as a therapeutic has shown clinical promise. We screened a collection of diverse
Jorge Meneses Nunes et al.
Antimicrobial agents and chemotherapy, 57(1), 382-389 (2012-11-02)
Rhodotorula species are emergent fungal pathogens capable of causing invasive infections, primarily fungemia. They are particularly problematic in immunosuppressed patients when using a central venous catheter. In this study, we evaluated the species distribution of 51 clinical and 8 environmental
Gentian violet - A blessing in disguise for the developing world.
Syed Arsalan Ali et al.
Burns : journal of the International Society for Burn Injuries, 39(6), 1326-1327 (2013-03-08)
David Brunn et al.
Cancers, 13(2) (2021-01-13)
Transcription factors can serve as links between tumor microenvironment signaling and oncogenesis. Interferon regulatory factor 9 (IRF9) is recruited and expressed upon interferon stimulation and is dependent on cofactors that exert in tumor-suppressing or oncogenic functions via the JAK-STAT pathway.
Manisha Taya et al.
Endocrine-related cancer, 27(4), 261-274 (2020-02-12)
Chronic inflammation promotes progression of many cancers, with circulating myeloid-derived suppressor cell (MDSC) levels correlating with poor prognosis. Here we examine effects of MDSCs on lymphangioleiomyomatosis (LAM), a rare disease occurring almost exclusively in women whereby estrogen-sensitive metastatic TSC2-null tumors
K Engbaek et al.
Journal of clinical pathology, 32(2), 187-190 (1979-02-01)
Five techniques for Gram staining bacteria in paraffin sections were compared on serial sections of pulmonary tissues from eight bacteriological necropsies. Brown and Hopp's method was the most satisfactory for distinguishing Gram-positive and Gram-negative bacteria. However, this method cannot be
Marie-Anaïs Locquet et al.
Cells, 10(2) (2021-03-07)
Chordomas are rare, slow-growing tumors of the axial skeleton. These tumors are locally aggressive and refractory to conventional therapies. Radical surgery and radiation remain the first-line treatments. Despite these aggressive treatments, chordomas often recur and second-line treatment options are limited.
Yunmee Lho et al.
International journal of molecular sciences, 22(9) (2021-05-06)
We investigated the effectiveness of the transforming growth factor beta-1 (TGF-β) receptor inhibitor GW788388 on the epithelial to mesenchymal transition (EMT) using human peritoneal mesothelial cells (HPMCs) and examined the effectiveness of GW788388 on the peritoneal membrane using a peritoneal
Performance of Gram and Acridine-orange staining in hand phlegmon.
Camillo Theo Müller et al.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 67(10), 1451-1452 (2014-06-11)
Ningbo Liu et al.
Respiratory research, 20(1), 230-230 (2019-10-28)
In mammalian cells, Aurora serine/threonine kinases (Aurora A, B, and C) are expressed in a cell cycle-dependent fashion as key mitotic regulators required for the maintenance of chromosomal stability. Aurora-A (AURKA) has been proven to be an oncogene in a
Yumi Fujimoto et al.
Scientific reports, 10(1), 21762-21762 (2020-12-12)
Amplification and/or overexpression of human epidermal growth factor receptor 2 (HER2) are observed in 15-20% of breast cancers (HER2+ breast cancers), and anti-HER2 therapies have significantly improved prognosis of patients with HER2+ breast cancer. One resistance mechanism to anti-HER2 therapies
Nicole Praska et al.
Forensic science international, 224(1-3), 51-58 (2012-11-28)
We explored whether an undeveloped latent print (fingermark) exposed to blood and later developed by enhancement with blood reagents such as amido black (AB) or leucocrystal violet (LCV) could appear as a genuine blood mark. We examined three different experimental
Olivier Clerc et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 56(8), 1101-1107 (2012-12-25)
Early identification of pathogens from blood cultures using matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry may optimize the choice of empirical antibiotic therapy in the setting of bloodstream infections. We aimed to assess the impact of this new technology
Jeonghwan Youk et al.
Cell stem cell, 27(6), 905-919 (2020-11-04)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the cause of a present pandemic, infects human lung alveolar type 2 (hAT2) cells. Characterizing pathogenesis is crucial for developing vaccines and therapeutics. However, the lack of models mirroring the cellular
Dai Miyazaki et al.
Nippon Ganka Gakkai zasshi, 117(4), 351-356 (2013-06-19)
To evaluate the efficacy of Gram-Fungiflora Y double staining for corneal scraping samples collected by impression in diagnosing infectious keratitis. Two hundred and thirteen eyes of 192 patients suspected of having infectious keratitis were retrospectively studied for the sensitivity and
Youngjae Ryu et al.
International journal of molecular sciences, 22(3) (2021-02-03)
Polycystic ovarian syndrome (PCOS) is a common reproductive endocrine disorder in reproductive-age women. Due to its various pathophysiological properties and clinical heterophenotypes, the mechanism of PCOS pathogenesis is still unclear. Several animal models have been used to study PCOS and
Ricardo L Berrios et al.
Dermatologic clinics, 29(1), 69-73 (2010-11-26)
The term pyoderma encompasses a variety of distinct entities including impetigo (bullous and nonbullous), erysipelas, cellulitis, folliculitis, and staphylococcal scalded skin syndrome. Treatment of pyodermas centers around wound care and appropriate antibiotic selection. Triphenylmethane dyes, such as gentian violet, represent
Jinsoo Yoon et al.
Methods and protocols, 3(1) (2020-01-26)
Bioluminescent tumor cell lines are used extensively in vivo to monitor tumor growth and metastasis but rarely used in vitro to follow tumor cell behavior. Tumor cell migration is frequently studied in vitro using transwell assays, however, current methods do
Characterization of potent and selective iodonium-class inhibitors of NADPH oxidases
Lu J, et al.
Biochemical Pharmacology, 43, 25-38 (2017)
Uri Ben-David et al.
Nature communications, 7, 12160-12160 (2016-07-05)
Aneuploidy and copy-number alterations (CNAs) are a hallmark of human cancer. Although genetically engineered mouse models (GEMMs) are commonly used to model human cancer, their chromosomal landscapes remain underexplored. Here we use gene expression profiles to infer CNAs in 3,108
Ming Chang et al.
Frontiers in pharmacology, 12, 758219-758219 (2021-10-12)
Litchi seeds have been traditionally used in Chinese herbal formula for urologic neoplasms including prostate cancer (PCa). However, the effective components of Litchi seeds and the mechanisms of their actions on PCa cell growth and metastasis remain unclear. In this
Alexis Laurent et al.
Frontiers in bioengineering and biotechnology, 8, 581-581 (2020-07-09)
Cultured primary progenitor cell types are worthy therapeutic candidates for regenerative medicine. Clinical translation, industrial transposition, and commercial implementation of products based on such cell sources are mainly hindered by economic or technical barriers and stringent regulatory requirements. Applied research
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