- Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States.
Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States.
Antimicrobial agents and chemotherapy (2008-04-23)
Andrea Endimiani, Lenore L Carias, Andrea M Hujer, Christopher R Bethel, Kristine M Hujer, Federico Perez, Rebecca A Hutton, William R Fox, Geraldine S Hall, Michael R Jacobs, David L Paterson, Louis B Rice, Stephen G Jenkins, Fred C Tenover, Robert A Bonomo
PMID18426899
ABSTRACT
The presence of plasmid-mediated quinolone resistance genes [i.e., qnrA, qnrB, qnrS, aac(6')-Ib-cr, and qepA] was evaluated among 42 bla(KPC)-containing Klebsiella pneumoniae isolates collected in the eastern United States. One isolate carried the bla(KPC-3) and qnrB19 genes on the same conjugative plasmid, whereas another carried the bla(KPC-3) and qnrA1 genes on separate plasmids.
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