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  • Ultrasound guided neural stem cell transplantation through the lateral ventricle for treatment of cerebral palsy in children.

Ultrasound guided neural stem cell transplantation through the lateral ventricle for treatment of cerebral palsy in children.

Neural regeneration research (2012-11-15)
Sheng He, Zuo Luan, Suqing Qu, Xuan Qiu, Daqing Xin, Wenkai Jia, Yanhua Shen, Zehui Yu, Tao Xu
ABSTRACT

A total of 24 children with cerebral palsy were enrolled in this study and underwent ultrasound guided transplantation of neural stem cells through the lateral ventricle. Neural stem cells (3.8 × 10(6)-7.3 × 10(7)) were injected into the lateral ventricles. Mild injury of lateral ventricular blood vessels occurred in only two cases (8.3%). Seven cases (29.2%) experienced a fever. Clinical manifestations were improved to varying degrees in eight cases (28.0%) within 3 months after transplantation. Patient condition did not worsen, and no patient experienced severe adverse reactions.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5, ascites fluid, clone GA5, Chemicon®