Neocuproine-KOtBu promoted intramolecular cross coupling to approach fused rings.

Neocuproine-KOtBu promoted intramolecular cross coupling to approach fused rings.

Chemical communications (Cambridge, England) (2011-08-10)

Chang-Liang Sun, Yi-Fan Gu, Wei-Ping Huang, Zhang-Jie Shi

ABSTRACT

Polycycles can be produced with different linkages (A, B = O, N, C, S) by constructing biaryl C-C bonds via neocuproine-KO(t)Bu promoted cross coupling between C-Xs and C-Hs.

MATERIALS

Product Number

Brand

Product Description

N1501

Sigma-Aldrich

Neocuproine, ≥98%

659878

Sigma-Aldrich

Potassium tert-butoxide, sublimed grade, 99.99% trace metals basis

328650

Sigma-Aldrich

Potassium tert-butoxide solution, 1.0 M in THF

156671

Sigma-Aldrich

Potassium tert-butoxide, reagent grade, ≥98%