Skip to Content
Merck
CN
  • In vitro antifungal activity of terpinen-4-ol, eugenol, carvone, 1,8-cineole (eucalyptol) and thymol against mycotoxigenic plant pathogens.

In vitro antifungal activity of terpinen-4-ol, eugenol, carvone, 1,8-cineole (eucalyptol) and thymol against mycotoxigenic plant pathogens.

Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment (2012-01-20)
C Morcia, M Malnati, V Terzi
ABSTRACT

The aim of this study was to examine the effect of five naturally occurring compounds from essential oils on 10 different species of mycotoxigenic fungi involved in several plant diseases. The antifungal activities of terpinen-4-ol, eugenol, carvone, 1,8-cineole (eucalyptol) and thymol were observed in vitro on Fusarium subglutinans, Fusarium cerealis, Fusarium verticillioides, Fusarium proliferatum, Fusarium oxysporum, Fusarium sporotrichioides, Aspergillus tubingensis, Aspergillus carbonarius, Alternaria alternata and Penicillium sp. The naturally occurring compounds tested showed toxic effects on in vitro mycelium growth of all fungal species but with different level of potency. The results are encouraging for further investigations of in planta antifungal activities of these essential oils components.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
L-Carvone, ≥97%, FCC, FG
Sigma-Aldrich
4-Carvomenthenol, ≥95%, FCC, FG
Sigma-Aldrich
4-Carvomenthenol, natural, ≥95%, FG
Sigma-Aldrich
L-Carvone, natural, 99%, FG
Sigma-Aldrich
D-Carvone, ≥96%, FG
Supelco
(+)-Carvone, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
Terpinen 4-ol, primary reference standard
Supelco
(−)-Carvone, analytical standard
Sigma-Aldrich
(S)-(+)-Carvone, 96%
Supelco
(+)-Carvone, analytical standard
Sigma-Aldrich
(R)-(−)-Carvone, 98%