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Bioactive oleanane, lupane and ursane triterpene acid derivatives.

Molecules (Basel, Switzerland) (2012-10-19)
Maria de L e Silva, Juceni P David, Lidércia C R C Silva, Rauldenis A F Santos, Jorge M David, Luciano S Lima, Pedro S Reis, Renato Fontana
ABSTRACT

Betulinic, ursolic and oleanolic acids isolated from the aerial parts of Eriope blanchetii (Lamiaceae) were subjected to different esterification reactions, yielding 12 C-3 position ester derivatives. All compounds were identified using spectroscopic techniques, such as IR, 1H-NMR and MS. The derivatives were further investigated for their antioxidant level, Artemia salina lethality and antimicrobial activity.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Betulinic acid, ≥98% (HPLC)
Supelco
Betulinic acid, analytical standard
Sigma-Aldrich
Betulinic acid, technical grade, 90%
Sigma-Aldrich
Ursolic acid, ≥90%
Supelco
Ursolic acid, analytical standard
Ursolic acid, primary reference standard