- N-Aminoindoline derivatives as inhibitors of 5-lipoxygenase.
N-Aminoindoline derivatives as inhibitors of 5-lipoxygenase.
Bioorganic & medicinal chemistry letters (2001-03-30)
C Audouin, N Mestdagh, M A Lassoie, R Houssin, J P Hénichart
PMID11277534
ABSTRACT
N-Aminoindoline derivatives were prepared and their 5-lipoxygenase inhibitory activities were evaluated in vitro and compared with those of phenidone and NDGA. Compound 4 presents the most effective 5-LO inhibition.
MATERIALS