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127914

1-Phenyl-3-pyrazolidinone

Name: 1-Phenyl-3-pyrazolidinone
Brand: ALDRICH

97%

Synonym(s):

Phenidone

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About This Item

Empirical Formula (Hill Notation):

C₉H₁₀N₂O

CAS Number:

92-43-3

Molecular Weight:

162.19

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24847805

EC Number:

202-155-1

Beilstein/REAXYS Number:

131856

MDL number:

MFCD00003094

Assay:

97%

Form:

powder

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Properties

Quality Level

100

assay

97%

form

powder

mp

119-121 °C (lit.)

SMILES string

O=C1CCN(N1)c2ccccc2

InChI

1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)

InChI key

CMCWWLVWPDLCRM-UHFFFAOYSA-N

Gene Information

rat ... Alox5(25290)

Description

Application

1-Phenyl-3-pyrazolidinone was used as a photograph developing agent.

pictograms

GHS07,GHS09

signalword

Warning

hcodes

H302,H411

pcodes

P264 - P270 - P273 - P301 + P312 - P391 - P501

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

275.5 °F - Pensky-Martens closed cup

flash_point_c

135.3 °C - Pensky-Martens closed cup

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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The Oxidation of 1-Phenyl-4, 4-dimethyl-3-pyrazolidinone in Alkaline Solution.

The Journal of Organic Chemistry, 30(8), 2571-2575 (1965)

Phenidone prevents kainate-induced neurotoxicity via antioxidant mechanisms.

H C Kim et al.

Brain research, 874(1), 15-23 (2000-08-11)

Acculmulating evidence indicates that a marked generation of oxygen free radicals derived from the metabolism of arachidonic acid causes neurodegeneration. Recently, we have demonstrated that the novel antioxidant actions mediated by phenidone, a dual inhibitor of cyclooxygenase/lipoxygenase pathways, may play

Oxidative damage in fetal rat brain induced by ischemia and subsequent reperfusion. Relation to arachidonic acid peroxidation.

A Wakatsuki et al.

Biology of the neonate, 76(2), 84-91 (1999-07-08)

To determine whether ischemia followed by subsequent reperfusion can induce fetal cerebral oxidative damage, we created a model of fetal ischemia/reperfusion using rats at day 19 of pregnancy. Fetal ischemia was induced by unilateral occlusion of the utero-ovarian artery for

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Global Trade Item Number

SKU	GTIN
127914-25G	04061838725257
127914-100G	04061838725240