The association between resistance exercise and cardiovascular disease risk in women.

The objective of this study was to examine the association between resistance exercise and cardiovascular disease risk, independent of body composition, physical activity and aerobic capacity, in healthy women. A cross-sectional analysis including 7321 women with no history of heart disease, hypertension or diabetes was performed. Participation in resistance exercise was self-reported and body weight and height was measured. A single cardiovascular disease risk score was established via factor analysis including percent body fat, mean arterial pressure, fasting glucose, total cholesterol and triglyceride levels. Physical activity level was determined based on questionnaire data and aerobic capacity was assessed via a maximal treadmill exercise test. Women reporting resistance exercise had lower total cardiovascular disease risk at any age. Specifically, resistance exercise was associated with lower body fat, fasting glucose and total cholesterol. The association between resistance exercise and cardiovascular disease risk, however, remained only in normal weight women after adjusting for physical activity and aerobic capacity. Results of the present study underline the importance of resistance exercise as part of a healthy and active lifestyle in women across all ages. Our results suggest that resistance exercise may be particularly beneficial to independently improve cardiovascular disease risk profiles in women with normal weight. In overweight/obese women, total physical activity and aerobic capacity may have a stronger association with cardiovascular disease risk.