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  • T cell receptor β-chains display abnormal shortening and repertoire sharing in type 1 diabetes.

T cell receptor β-chains display abnormal shortening and repertoire sharing in type 1 diabetes.

Nature communications (2017-11-28)
Iria Gomez-Tourino, Yogesh Kamra, Roman Baptista, Anna Lorenc, Mark Peakman
ABSTRACT

Defects in T cell receptor (TCR) repertoire are proposed to predispose to autoimmunity. Here we show, by analyzing >2 × 10

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Human Serum, from human male AB plasma, USA origin, sterile-filtered
Sigma-Aldrich
Staphylococcal enterotoxin B from Staphylococcus aureus