Merck
CN

PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

别名:
COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
物种:
UniProtKB ID:
基因ID:
  • Human(5743) Summary: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
  • Mouse(19225) prostaglandin-endoperoxide synthase 2
  • Rat(29527) prostaglandin-endoperoxide synthase 2
  • Goat(100860905) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • cow(282023) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Horse(791253) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic cat(100126581) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • dog(442942) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Domestic Rabbit(100009248) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • sheep(443460) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • naked mole-rat(101704771) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • chicken(396451) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic guinea pig(100135607) prostaglandin-endoperoxide synthase 2

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ELISA

货号
说明
物种
人COX-2 ELISA试剂盒, for cell culture supernatants, plasma, and serum samples,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-COX-2 antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM348, purified immunoglobulin,
物种反应性
human
应用
immunohistochemistry
抗-COX2 兔抗, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Cyclooxygenase-2 Antibody, Chemicon®, from rabbit,
物种反应性
bovine, human, mouse, sheep
应用
ELISA
western blot
Anti-Cox2 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
抗-COX2 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

Small Molecule - Blocker

货号
说明
物种
N--甲苯磺酰基-L-苯基乙基氯甲基酮, ≥97% (TLC), powder,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
塞来昔布, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
依托考昔, VETRANAL®, analytical standard,
物种
human
Aceclofenac, ≥98% (HPLC),
物种
human
卡洛芬, ≥97% (HPLC),
物种
human
塞来昔布, United States Pharmacopeia (USP) Reference Standard,
物种
human

Proteins

货号
说明
物种
环氧化酶 2 人, ≥70% (SDS-PAGE), recombinant, expressed in insect cells, aqueous solution, ≥8000 units/mg protein,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PTGS2,
物种
human
MISSION® esiRNA, targeting mouse Ptgs2,
物种
mouse