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Merck
CN

CDH1

cadherin 1, type 1, E-cadherin (epithelial)

别名:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
物种:
UniProtKB ID:
基因ID:
  • Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
  • Mouse(12550) cadherin 1
  • Rat(83502) cadherin 1
  • dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
  • chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
  • naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
  • Zebrafish(114424) cadherin 1, epithelial
  • cow(282637) cadherin 1, type 1, E-cadherin (epithelial)

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ELISA

Product Number
说明
物种
小鼠上皮钙粘附素 ELISA 试剂盒, for serum, plasma and cell culture supernatant,
物种
human

Antibodies

Product Number
说明
物种反应性
应用
抗E钙粘蛋白抗体, serum, Upstate®,
物种反应性
human
应用
immunohistochemistry
western blot
抗 E-钙黏蛋白 兔抗, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
抗-E-钙粘蛋白抗体(兔), ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
抗E钙粘蛋白抗体,克隆67A4,不含叠氮化物, clone 67A4, Chemicon®, from mouse,
物种反应性
human
应用
flow cytometry
immunofluorescence
抗-CDH1 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry

Cell Lines

Product Number
说明
物种
MCF10A CELLS CDH1 (-/-), ,
物种
human

Proteins

Product Number
说明
物种
E-钙粘素 人, recombinant, expressed in E. coli, 0.5 mg protein/mL,
物种
human
E-Cadherin/Fc Chimera from mouse, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
物种
mouse

esiRNA

Product Number
说明
物种
MISSION® esiRNA, targeting human CDH1,
物种
human
MISSION® esiRNA, targeting mouse Cdh1,
物种
mouse