By Design
Tools for mRNA synthesis for vaccine and
therapeutic development
mRNA Synthesis
mRNA synthesis plays a critical role in the early discovery and development of mRNA-based vaccines and therapeutics. The foundational step in the design and testing of mRNA candidates is precise and efficient in vitro transcription (IVT), enabling rapid prototyping of mRNA constructs that encode for therapeutic proteins or antigens of interest. Efficient IVT accelerates preclinical evaluation, facilitates high-throughput screening of sequences for stability and translational efficiency, and supports the iterative optimization necessary to identify promising candidates.
We provide a comprehensive portfolio to support mRNA synthesis. Our in vitro transcription reagents are designed to provide quality, scalable reagents with a strong global supply chain.
- Quality: Consistent, high-quality results with optimized standalone reagents and kits.
- Scalability: Solutions for both small-scale research and large-scale production.
- Flexibility: Offerings available in a variety of component and ready-made formats.
Reliable Reagents for Molecular Cloning and Plasmid Preparation
Essential tools for plasmid prep to ensure efficient template generation for high-quality mRNA synthesis.
Cloning and Expression
Plasmid Prep Kits
High Performance Enzymes, Nucleotides, and Buffers for mRNA Transcription
Our selection of IVT enzymes, reagents, and buffers is designed to deliver optimal results in RNA synthesis. Explore top-of-the-line products, including enzymes and reagents for high-performance transcription, as well as specially formulated buffers that enhance RNA synthesis efficiency and provide robust support for your experiments.
In Vitro Transcription Reagents
Transcription Buffers
Comprehensive Tools for mRNA Analysis and Quality Control
Ensure the accuracy and integrity of your RNA workflows with our complete suite of products tailored for every stage of mRNA analysis - from sequence confirmation to impurity detection. Enhance quality post-IVT with the GenElute™-E RNA Cleanup Kit—delivering high-purity mRNA free of contaminants for reliable RT-PCR and NGS results.
mRNA Cleanup and Purification
mRNA Identity
mRNA Integrity
RNA Content
Innovative Solutions for mRNA-LNP Optimization
Lipid nanoparticles (LNPs) are critical vehicles for mRNA delivery - encapsulating and conveying mRNA safely to cells. LNP selection is integral at the earliest stages of vaccine and therapeutic mRNA delivery research. We provide advanced tools designed to support LNP selection and rapid formulation screening, enabling efficient mRNA-LNP recovery for preclinical research.
Lipids for research and formulation development
Non-GMP lipids are ideal for use in mRNA targeting and delivery research, such as cationic lipids, PEG and structural lipids, and cholesterol.
Microfluidic chips and kits for formulation screening and optimization
NanoFabTx™ reagent and microfluidic device kits provide a ready-to-use platform to screen multiple formulations, and ultimately synthesize mRNA or drug-encapsulated liposomes for preclinical assessments.
Centrifugal filters for mRNA-LNP purification
Amicon® Ultra Filters are trusted for high-performance concentration and purification, ensuring high recovery of mRNA-LNP formulations.
Watch On-demand Panel Discussion: Revolutionizing Lipid-Based Delivery with Advances in Cell Models and Lipid Technology
Related Categories
Identify novel therapeutic targets using genome-wide functional genomics screening tools.
Transfection reagents for DNA, siRNA, miRNA, and CRISPR/Cas9 gene editing components.
An extensive collection of reagents for DNA and RNA gel electrophoresis and blotting.
Related Articles
- CRISPR Cas 9 Nuclease RNA-guided Genome Editing
CRISPR strategies and mRNA delivery of Cas9 gene editing.
- Reverse Transcription
RT-PCR guidelines and challenges including mRNA stability, temporal transcription patterns, and mRNA-protein correlation.
Explore our Products and Services
Tools for mRNA Antigen Discovery, mRNA Profiling, mRNA Synthesis, and mRNA Delivery
Tools for Pathogen Analysis, Validation Tools and Reagents, and mRNA Design and Optimization
mRNA Screening Tools, Predictive Biological Models, and Tools for Immune Response
如要继续阅读，请登录或创建帐户。
暂无帐户？