Uncover Your Next Target
Tools for mRNA Antigen Discovery
Antigen Discovery Products
Identification of a specific target antigen is a crucial step in mRNA vaccine development. We offer tools for genomics analysis, protein analysis, and antibody screening techniques to provide a comprehensive approach to antigen discovery.
Pathogen and Target Antigen Identification
Understanding your pathogen at the genomic and transcriptomic level is critical for selecting the right target antigen.
Key Tools for Pathogen Analysis
SeqPlex™-I Whole Genome and Whole Transcriptome Amplification Kits
Amplify viral or pathogen genomes and transcriptomes using SeqPlex™-I Whole Genome Amplification (WGA) and Whole Transcriptome Amplification (WTA) Kits for preparation in next-generation sequencing (NGS) workflows. These kits ensure robust coverage and high-quality sequencing data, providing the foundation for identifying target antigens.
MULTI-seq High-Throughput scRNA-seq Technology for Immune Response Mapping
Multiplexing single-cell analysis, particularly single-cell RNA sequencing (scRNA-seq), is a transformative tool for studying pathogens and their interactions with host cells. By enabling the simultaneous profiling of multiple samples or experimental conditions, multiplexing enhances the efficiency, scale, and depth of pathogen analysis.
Advantages of MULTI-seq technology:
- Increased Throughput: Pooling samples reduces the number of experiments required, conserving resources.
- Reduced Batch Effects: Shared processing of multiple samples minimizes technical variability.
- Cost Efficiency: By pooling, researchers can analyze more samples per sequencing run, reducing overall costs.
Once antigens are identified, their immunogenic potential must be confirmed through comprehensive testing.
Validation Tools and Reagents
Comprehensive Recombinant Protein Expression Systems
Express candidate antigens in bacterial, yeast, insect, mammalian, or cell-free systems, each providing flexibility and optimized protein production.
Antibodies for Protein Characterization
Detect, analyze, and validate protein-protein interactions with high quality antibodies to ensure antigen functionality.
Western Blotting
Screen and identify antigen candidates efficiently using our Electrophoresis and Western blotting reagents to prioritize those most likely to elicit an immune response.
ELISA
Screen antigens for immunogenicity and assess antibody binding potential with reliable tools including ELISA-validated antibodies, ELISA kits, and MultiScreen® ELISA high-binding plates.
mRNA Design and Optimization
Engineer your validated antigen into a translatable mRNA construct for vaccine development with innovative solutions for mRNA expression.
Simplicon™ In Vivo Protein Expression System
Our Simplicon™ In Vivo Protein Expression System is a novel, self-replicative RNA-based system for immediate and sustained protein expression into transiently transfected human cells. Ideal for validating antigen constructs in a natural cellular environment.
Related Categories
Prep for next-gen sequencing with tools designed to simplify workflows for high quality libraries.
Multiplexed scRNA-seq for gene expression analysis.
Primary and secondary antibodies and antibody conjugates for ELISA and immunoassay.
Reagents, consumables, and equipment for electrophoresis and detection.
Rapid, quantitative, and sensitive analyte detection at low cost.
Molecular cloning tools for reliable cloning and robust protein expression.
Related Resources
- mPAGE®Lux Casting System for SDS-PAGE Gels
Discover the mPAGE® Lux Casting System for ready-to-use SDS-PAGE gels in 3 minutes - fresh SDS-PAGE gels that are ready when you need them.
- Viral RNA Purification Protocol Using GenElute™ Mammalian Total RNA Purification Kits
Instructions for purifying viral RNA using GenElute™ Mammalian Total RNA Purification Kits.
- Quantitative RT-PCR
RT-qPCR products combine the effective of Reverse Transcriptase with hot-start taq-directed antibody in convenient ReadyMixes for probe-based or SYBR® Green based applications.
- Gel Electrophoresis with mPAGE® Gels
Gel Electrophoresis with mPAGE® Precast Gels under mPAGE® Lux Cast System for SDS-PAGE Gels.
Explore Our Products & Services
Tools for mRNA Antigen Discovery, mRNA Profiling, mRNA Synthesis, and mRNA Delivery
mRNA Screening Tools, Predictive Biological Models, and Tools for Immune Response
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