Merck
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文件

42995

Sigma-Aldrich

反式-1,3-二苯基-2,3-环氧丙-1-酮

≥98.0%

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别名:
反式-2-苯甲酰基-3-苯基环氧乙烷, 反式-亚苄基乙酰苯氧化物
经验公式（希尔记法）:
C15H12O2
CAS号:
7570-86-7
分子量:
224.25
Beilstein:
84132
MDL编号:
MFCD00066320
PubChem化学物质编号:
57650138
NACRES:
NA.22

检测方案

≥98.0%

形式

solid

mp

86-89 °C (lit.)

SMILES string

O=C([C@H]1O[C@@H]1c2ccccc2)c3ccccc3

InChI

1S/C15H12O2/c16-13(11-7-3-1-4-8-11)15-14(17-15)12-9-5-2-6-10-12/h1-10,14-15H/t14-,15-/m1/s1

InChI key

UQGMJZQVDNZRKT-HUUCEWRRSA-N

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相关类别

一般描述

trans-1,3-Diphenyl-2,3-epoxypropan-1-one has been reported to efficiently participate in gas-phase Meerwein reaction under both electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) conditions. Therapeutic potential of trans-1,3-diphenyl-2,3-epoxypropane-1-one (DPEP), and its anti-inflammatory effects have been studied.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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Giulia Licini et al.
Biopolymers, 84(1), 97-104 (2005-08-27)
C(alpha)-tetrasubstituted alpha-amino acids constitute a powerful tool for controlling the conformation of short peptide sequences. Chiral peptides may be used in stereoselective reactions both for asymmetric induction and in kinetic resolution. By reviewing recent data from our own laboratories and
E C Dietze et al.
Biochemical pharmacology, 42(6), 1163-1175 (1991-08-22)
The inhibition of murine cytosolic epoxide hydrolase has been studied with both racemic and enantiomerically pure trans-3-phenylglycidols. These compounds are the first enantioselective, slow binding inhibitors of cytosolic epoxide hydrolase. The (2S,3S)-3-phenylglycidol enantiomer was always a better inhibitor than the
Chalcone oxides--potent selective inhibitors of cytosolic epoxide hydrolase.
C A Mullin et al.
Archives of biochemistry and biophysics, 216(2), 423-439 (1982-07-01)
A D Marshall et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 30(6), 467-473 (1992-06-01)
The effect of modulating epoxide metabolism by inhibiting microsomal and cytosolic epoxide hydrolases and depleting glutathione, on the cytotoxicity of trans-anethole has been examined in freshly isolated rat hepatocytes in suspension. Hepatocytes derived from female Sprague-Dawley CD rats by collagenase
David R Kelly et al.
Chemical communications (Cambridge, England), (18)(18), 2021-2022 (2004-09-16)
Polyleucine prepared from scalemic Leu-NCA monomers, shows high chiral amplification in the Julia-Colonna epoxidation of chalcone.
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