Merck
CN
所有图片(3)

文件

651699

Sigma-Aldrich

1-（1-萘甲基）哌嗪

95%

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经验公式（希尔记法）:
C15H18N2
CAS号:
40675-81-8
分子量:
226.32
MDL编号:
MFCD01314185
PubChem化学物质编号:
24883855
NACRES:
NA.22

检测方案

95%

形式

solid

mp

63-67 °C (lit.)

SMILES string

C1CN(CCN1)Cc2cccc3ccccc23

InChI

1S/C15H18N2/c1-2-7-15-13(4-1)5-3-6-14(15)12-17-10-8-16-9-11-17/h1-7,16H,8-12H2

InChI key

HGYDREHWXXUUIS-UHFFFAOYSA-N

相关类别

象形图

Exclamation markEnvironment
GHS07,GHS09

警示用语：

Warning

危险分类

Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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Jun-Ren Sun et al.
PloS one, 7(11), e49534-e49534 (2012-11-21)
Over-expression of AdeABC efflux pump stimulated continuously by the mutated AdeRS two component system has been found to result in antimicrobial resistance, even tigecycline (TGC) resistance, in multidrug-resistant Acinetobacter baumannii (MRAB). Although the insertion sequence, ISAba1, contributes to one of
Zachary P Howard et al.
Infection and immunity, 88(12) (2020-09-16)
Coxiella burnetii is a zoonotic bacterial obligate intracellular parasite and the cause of query (Q) fever. During natural infection of female animals, C. burnetii shows tropism for the placenta and is associated with late-term abortion, at which time the pathogen
João Anes et al.
Frontiers in microbiology, 10, 92-92 (2019-03-01)
Antimicrobial efflux is one of the important mechanisms causing multi-drug resistance (MDR) in bacteria. Chemosensitizers like 1-(1-naphthylmethyl)-piperazine (NMP) can inhibit an efflux pump and therefore can overcome MDR. However, secondary effects of NMP other than efflux pump inhibition are rarely
Ram Prosad Chakrabarty et al.
AMB Express, 6(1), 126-126 (2016-12-23)
The study aims at revealing the comprehensive contribution of target alteration, target protection and efflux pump to the development of high level of ciprofloxacin (CIP) resistance in Enterobacteriaceae bacteria of environmental, clinical and poultry origins. Antibiotic susceptibility test was used
Sabine Schuster et al.
International journal of antimicrobial agents, 50(3), 477-481 (2017-07-12)
Drug efflux by resistance-nodulation-cell division (RND)-type transporters, such as AcrAB-TolC of Escherichia coli, is an important resistance mechanism in Gram-negative bacteria; however, its contribution to multidrug resistance (MDR) in clinical isolates is poorly defined. We inactivated acrB of a sequence
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