Dibenzocyclooctyne-PEG4-acid

Name: Dibenzocyclooctyne-PEG4-acid
Brand: ALDRICH

for Copper-free Click Chemistry

别名:

Polyethylene glycol, DBCO-PEG4-Acid

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所有图片(1)

About This Item

经验公式（希尔记法）:

C₃₂H₄₀N₂O₈

分子量:

580.67

MDL编号:

MFCD22380749

UNSPSC代码:

12352106

PubChem化学物质编号:

329766822

NACRES:

NA.22

质量水平

100

表单

solid

反应适用性

reaction type: click chemistry
reagent type: linker

官能团

carboxylic acid

储存温度

−20°C

SMILES字符串

O=C(CCCCC(NCCOCCOCCOCCOCCC(O)=O)=O)N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3

InChI

1S/C32H40N2O8/c35-30(33-16-18-40-20-22-42-24-23-41-21-19-39-17-15-32(37)38)11-5-6-12-31(36)34-25-28-9-2-1-7-26(28)13-14-27-8-3-4-10-29(27)34/h1-4,7-10H,5-6,11-12,15-25H2,(H,33,35)(H,37,38)

InChI key

RMYANOWYMFCGGS-UHFFFAOYSA-N

应用

Acid functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The PEG spacer adds hydrophilicity to the product to decrease aggregation.

Dibenzocyclooctyne-PEG4-acid may be used as a substrate in azide-cyclooctyne cycloaddition reactions.