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759902

Dibenzocyclooctyne-PEG4-acid

Name: Dibenzocyclooctyne-PEG4-acid
Brand: ALDRICH

for Copper-free Click Chemistry

别名:

Polyethylene glycol, DBCO-PEG4-Acid

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关于此项目

经验公式（希尔记法）:

C₃₂H₄₀N₂O₈

分子量:

580.67

NACRES:

NA.22

PubChem Substance ID:

329766822

UNSPSC Code:

12352106

MDL number:

MFCD22380749

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属性

Quality Level

100

form

solid

reaction suitability

reaction type: click chemistry, reagent type: linker

functional group

carboxylic acid

storage temp.

−20°C

SMILES string

O=C(CCCCC(NCCOCCOCCOCCOCCC(O)=O)=O)N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3

InChI

1S/C32H40N2O8/c35-30(33-16-18-40-20-22-42-24-23-41-21-19-39-17-15-32(37)38)11-5-6-12-31(36)34-25-28-9-2-1-7-26(28)13-14-27-8-3-4-10-29(27)34/h1-4,7-10H,5-6,11-12,15-25H2,(H,33,35)(H,37,38)

InChI key

RMYANOWYMFCGGS-UHFFFAOYSA-N

说明

Application

Dibenzocyclooctyne-PEG4-acid may be used as a substrate in azide-cyclooctyne cycloaddition reactions.

Acid functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The PEG spacer adds hydrophilicity to the product to decrease aggregation.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Karver MR, et al.

Angewandte Chemie (International Edition in English), 51(4), 920-922 (2012)

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Jianwen Xu et al.

Chemistry, an Asian journal, 6(10), 2730-2737 (2011-09-29)

Strategies to encapsulate cells in cytocompatible three-dimensional hydrogels with tunable mechanical properties and degradability without harmful gelling conditions are highly desired for regenerative medicine applications. Here we reported a method for preparing poly(ethylene glycol)-co-polycarbonate hydrogels through copper-free, strain-promoted azide-alkyne cycloaddition

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全球贸易项目编号

货号	GTIN
759902-50MG	04061833230435
759902-5MG	04061833230442