Quality Level
form
solid
reaction suitability
reaction type: click chemistry, reagent type: linker
functional group
carboxylic acid
storage temp.
−20°C
SMILES string
O=C(CCCCC(NCCOCCOCCOCCOCCC(O)=O)=O)N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3
InChI
1S/C32H40N2O8/c35-30(33-16-18-40-20-22-42-24-23-41-21-19-39-17-15-32(37)38)11-5-6-12-31(36)34-25-28-9-2-1-7-26(28)13-14-27-8-3-4-10-29(27)34/h1-4,7-10H,5-6,11-12,15-25H2,(H,33,35)(H,37,38)
InChI key
RMYANOWYMFCGGS-UHFFFAOYSA-N
Application
Dibenzocyclooctyne-PEG4-acid may be used as a substrate in azide-cyclooctyne cycloaddition reactions.
Acid functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The PEG spacer adds hydrophilicity to the product to decrease aggregation.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
商品
Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.
无铜点击化学是点击化学的一种替代方法,可在较低的活化屏障下进行,且没有细胞毒性过渡金属催化剂。
Bioorthogonal Reaction Pairs Enable Simultaneous, Selective, Multi?Target Imaging
Karver MR, et al.
Angewandte Chemie (International Edition in English), 51(4), 920-922 (2012)
Jianwen Xu et al.
Chemistry, an Asian journal, 6(10), 2730-2737 (2011-09-29)
Strategies to encapsulate cells in cytocompatible three-dimensional hydrogels with tunable mechanical properties and degradability without harmful gelling conditions are highly desired for regenerative medicine applications. Here we reported a method for preparing poly(ethylene glycol)-co-polycarbonate hydrogels through copper-free, strain-promoted azide-alkyne cycloaddition
A Versatile Monomer for Preparing Well-Defined Functional Polycarbonates and Poly(estercarbonates)
Xu J.; et al.
Macromolecules, 44, 2260-2267 (2011)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 759902-50MG | 04061833230435 |
| 759902-5MG | 04061833230442 |