Quality Level
assay
95%
form
solid
reaction suitability
reaction type: click chemistry, reagent type: linker
mp
118-125 °C
functional group
carboxylic acid
storage temp.
−20°C
SMILES string
O=C(CCCCC(O)=O)N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3
InChI
1S/C21H19NO3/c23-20(11-5-6-12-21(24)25)22-15-18-9-2-1-7-16(18)13-14-17-8-3-4-10-19(17)22/h1-4,7-10H,5-6,11-12,15H2,(H,24,25)
InChI key
NIRLBCOFKPVQLM-UHFFFAOYSA-N
General description
酸官能化的环辛炔衍生物。环辛炔可用于应变促进的无铜叠氮化物-炔烃点击化学反应。该氮杂二苯并环辛炔可与叠氮官能化化合物或生物分子发生反应，而不需要Cu(I) 催化剂以产生稳定的三唑键。
Application
二苯并环辛炔酸可用于八臂聚（乙二醇）的表面改性，使易于与PEG-双叠氮化物应变促进炔-叠氮化物环加合（SPAAC），以导致水凝胶的形成。这些水凝胶可用于蛋白质固定。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Ratiometric Fluorescence Azide?Alkyne Cycloaddition for Live Mammalian Cell Imaging.
Fu H, et al.
Analytical Chemistry, 87(22), 11332-11336 (2015)
Chen Guo et al.
Acta biomaterialia, 56, 80-90 (2017-04-10)
Hydrogels are facile architectures for the controlled presentation of proteins with far-reaching applications, from fundamental biological studies in three-dimensional culture to new regenerative medicine and therapeutic delivery strategies. Here, we demonstrate a versatile approach for spatially-defined presentation of engineered proteins
Seyed Mohammad Mahdi Dadfar et al.
Small (Weinheim an der Bergstrasse, Germany), 14(21), e1800131-e1800131 (2018-04-24)
Different types of click chemistry reactions are proposed and used for the functionalization of surfaces and materials, and covalent attachment of organic molecules. In the present work, two different catalyst-free click approaches, namely azide-alkyne and thiol-alkyne click chemistry are studied
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 761516-10MG | 04061833230596 |