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761524

二苯并环辛炔-N-羟基琥珀酰亚胺酯

Name: 二苯并环辛炔-<I>N</I>-羟基琥珀酰亚胺酯
Brand: ALDRICH

for Copper-free Click Chemistry

别名:

DBCO-NHS酯, DBCO-SE

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关于此项目

经验公式（希尔记法）:

C₂₃H₁₈N₂O₅

分子量:

402.40

NACRES:

NA.22

PubChem Substance ID:

329766555

UNSPSC Code:

12352108

MDL number:

MFCD24386367

Form:

solid

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属性

Quality Level

100

form

solid

reaction suitability

reaction type: click chemistry, reagent type: cross-linking reagent

mp

149-157 (decomposition)

functional group

NHS ester

storage temp.

−20°C

SMILES string

O=C(CCC(ON(C(CC1)=O)C1=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4

InChI

1S/C23H18N2O5/c26-20(13-14-23(29)30-25-21(27)11-12-22(25)28)24-15-18-7-2-1-5-16(18)9-10-17-6-3-4-8-19(17)24/h1-8H,11-15H2

InChI key

XCEBOJWFQSQZKR-UHFFFAOYSA-N

说明

General description

DBCO-NHS 酯常用于生物偶联。它由NHS酯组成，NHS酯可以与生物分子上的伯胺和炔基反应，该炔基导致与含叠氮化物分子的特异性反应。该反应通过一种称为应变促进炔烃-叠氮化物环加成的无铜点击化学过程进行。

Application

二苯并环辛炔- N -羟基琥珀酰亚胺酯常用于：

通过将DBCO基团引入其表面进行抗体和链霉亲和素等生物分子的修饰和标记
作为交联剂使抗原在聚乳酸-乙醇酸共聚物（PLGA）的表面结合。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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全球贸易项目编号

货号	GTIN
761524-5MG	04061833230602
761524-50MG	04061832918419