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764019

二苯基环辛炔-PEG4-氢化琥珀酰亚胺酯

≥90%

别名:

DBCO-PEG4-NHS酯, DBCO-PEG4-SE, DBCO-PEG4-氢化琥珀酰亚胺酯

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关于此项目

经验公式（希尔记法）:
C34H39N3O10
分子量:
649.69
NACRES:
NA.22
PubChem Substance ID:
329767092
UNSPSC Code:
12352108
MDL number:
MFCD26793797
Assay:
≥90%
Form:
paste
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Quality Level

100

assay

≥90%

form

paste

reaction suitability

reaction type: click chemistry, reagent type: linker

functional group

NHS ester

storage temp.

−20°C

SMILES string

O=C(CCC(NCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4

InChI

1S/C34H39N3O10/c38-30(11-12-31(39)36-25-28-7-2-1-5-26(28)9-10-27-6-3-4-8-29(27)36)35-16-18-44-20-22-46-24-23-45-21-19-43-17-15-34(42)47-37-32(40)13-14-33(37)41/h1-8H,11-25H2,(H,35,38)

InChI key

RRCXYKNJTKJNTD-UHFFFAOYSA-N

Application

聚乙二醇-PEG4-N-氢化琥珀酰亚胺酯可以通过少铜点击反应，用来合成前列腺特异性膜抗体（PSMA）目标单光子发射计算体层摄影（SPECT）试剂。
琥珀酰亚胺酯（NHS，胺反应活性）官能化环辛烷衍生物，用来将环辛烷部分插入含有化合物或生物分子的氨基找那个。环辛烷可以用于种促进免铜电极化学环加成反应。这一聚乙二醇会和叠氮官能化化合物或生物分子反应，而不需要Cu（I）催化，就能形成稳定的三唑连接。

应用包括：
  • 蛋白质-多肽偶联物
  • 抗体-酶或抗体药物偶联物
  • 蛋白质或多肽-寡核苷酸偶联物
  • 表面修饰

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKDB0773
MKDB0061
MKCZ9800
MKCZ8379
MKCZ8382

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Explore the principles and applications of click chemistry in drug discovery, highlighting efficient reactions that streamline the synthesis of bioactive compounds.

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全球贸易项目编号

货号GTIN
764019-5MG04061833230862
764019-50MG04061832922980
764019-1MG04061826701638