M-080
甲基丙二酸 溶液
1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
InChI key
ZIYVHBGGAOATLY-UHFFFAOYSA-N
InChI
1S/C4H6O4/c1-2(3(5)6)4(7)8/h2H,1H3,(H,5,6)(H,7,8)
SMILES string
CC(C(O)=O)C(O)=O
grade
certified reference material
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in acetonitrile
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
clinical testing
pharmaceutical (small molecule)
format
single component solution
storage temp.
−20°C
Quality Level
General description
甲基丙二酸是维生素B12 缺乏症和甲基丙二酸血症的指标。该经认证的加标溶液®适用于使用GC/MS或LC/MS制备临床和诊断测试中的校准品或质控品。
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
35.6 °F - closed cup
flash_point_c
2 °C - closed cup
法规信息
危险化学品
此项目有
Takayuki Watanabe et al.
Journal of feline medicine and surgery, 14(12), 942-945 (2012-08-22)
A 10-year-old domestic shorthair cat showed anorexia, lethargy and ptyalism with hyperammonaemia. Portosystemic shunts were not identified by computed tomography angiography. Biopsy results revealed mild interstinal nephritis and no lesion in the liver. Analysis of urine revealed the presence of
Carla Dullemeijer et al.
The American journal of clinical nutrition, 97(2), 390-402 (2012-12-28)
Many randomized controlled trials (RCTs) and observational studies have provided information on the association between vitamin B-12 intake and biomarkers. The use of these data to estimate dose-response relations provides a useful means to summarize the body of evidence. We
Acute renal failure potentiates methylmalonate-induced oxidative stress in brain and kidney of rats.
P F Schuck et al.
Free radical research, 47(3), 233-240 (2013-01-10)
Tissue methylmalonic acid (MMA) accumulation is the biochemical hallmark of methylmalonic acidemia. The disease is clinically characterized by progressive neurological deterioration and kidney failure, whose pathophysiology is still unclear. In the present work we investigated the effects of acute MMA
Setareh Shahab-Ferdows et al.
The Journal of nutrition, 142(10), 1881-1887 (2012-08-24)
A high prevalence of low serum vitamin B-12 concentrations has been reported in studies and surveys in Latin America including Mexico, but the functional consequences are unknown. This randomized controlled trial assessed the response to a high-dose vitamin B-12 supplementation
Yu-peng Liu et al.
Zhonghua er ke za zhi = Chinese journal of pediatrics, 50(6), 410-414 (2012-08-31)
Methylmalonic aciduria is the most common disorder of organic acidurias in the mainland of China. It is also the one of treatable metabolic disorders. The clinical spectrum of the patients varies from severe neonatal-onset forms with neonatal brain injury and
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