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Merck
CN

1.00201

苯酚

EMPROVE® ESSENTIAL, Ph. Eur., ChP, JP, USP

别名:

苯酚

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线性分子式:
C6H5OH
化学文摘社编号:
108-95-2
分子量:
94.11
EC Index Number:
203-632-7
UNSPSC Code:
12352104
Beilstein/REAXYS Number:
969616
MDL number:
MFCD00002143

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产品名称

苯酚, EMPROVE® ESSENTIAL, Ph. Eur., ChP, JP, USP

SMILES string

Oc1ccccc1

InChI

1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H

InChI key

ISWSIDIOOBJBQZ-UHFFFAOYSA-N

agency

ChP
JP
Ph. Eur.
USP

vapor density

3.24 (vs air)

vapor pressure

0.09 psi ( 55 °C)
0.36 mmHg ( 20 °C)

product line

EMPROVE® ESSENTIAL

assay

99.0-100.5% (bromatometric)

form

solid

autoignition temp.

1319 °F

expl. lim.

8.6 %

technique(s)

API processing | cocrystal formation: suitable

pH

5 (20 °C, 50 g/L in H2O)

bp

182 °C (lit.)

mp

40-42 °C (lit.)

transition temp

flash point 81 °C

density

1.071 g/mL at 25 °C (lit.)

application(s)

liquid formulation
pharma/biopharma processes
pharmaceutical

storage temp.

15-25°C

Quality Level

500

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相关类别

Application

Phenol is active against a wide range of microorganisms and is therefore used as a preservative in pharmaceutical formulations.

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - STOT RE 2

target_organs

Nervous system,Kidney,Liver,Skin

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 2

flash_point_f

177.8 °F - closed cup

flash_point_c

81 °C - closed cup

法规信息

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Criteria for Selecting Preservatives Used in Liquid Formulation

Find key considerations for the selection and use of preservatives in a range of different therapeutic applications including topical, oral, transmucosal, inhalation, and otic, as well as injectables.

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