Merck
CN
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文件

安全信息

1.00201

SAFC

苯酚

EMPROVE® ESSENTIAL, Ph. Eur., ChP, JP, USP

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别名:
苯酚
线性分子式:
C6H5OH
CAS号:
108-95-2
分子量:
94.11
Beilstein:
969616
MDL编号:
MFCD00002143
EC索引号:
203-632-7

Agency

ChP
JP
Ph. Eur.
USP

质量水平

500

蒸汽密度

3.24 (vs air)

蒸汽压

0.09 psi ( 55 °C)
0.36 mmHg ( 20 °C)

产品线

EMPROVE® ESSENTIAL

检测方案

99.0-100.5% (bromatometric)

形式

solid

自燃温度

1319 °F

expl. lim.

8.6 %

technique(s)

API processing | cocrystal formation: suitable

pH值（酸碱度）

5 (20 °C, 50 g/L in H2O)

bp

182 °C (lit.)

mp

40-42 °C (lit.)

转变温度

flash point 81 °C

密度

1.071 g/mL at 25 °C (lit.)

application(s)

liquid formulation
pharma/biopharma processes
pharmaceutical

储存温度

15-25°C

SMILES string

Oc1ccccc1

InChI

1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H

InChI key

ISWSIDIOOBJBQZ-UHFFFAOYSA-N

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相关类别

一般描述

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Phenol is active against a wide range of microorganisms and is therefore used as a preservative in pharmaceutical formulations.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - STOT RE 2

储存分类代码

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 2

闪点(°F)

177.8 °F - closed cup

闪点(°C)

81 °C - closed cup

法规信息

危险化学品

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商品

Criteria for Selecting Preservatives Used in Liquid Formulation

Find key considerations for the selection and use of preservatives in a range of different therapeutic applications including topical, oral, transmucosal, inhalation, and otic, as well as injectables.

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