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Merck
CN

1.00681

琥珀酸

crystalline, EMPROVE® ESSENTIAL, ChP, NF, JPE, ACS

别名:

丁二酸

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关于此项目

线性分子式:
HOOCCH2CH2COOH
化学文摘社编号:
110-15-6
分子量:
118.09
EC Index Number:
203-740-4
UNSPSC Code:
12352106
Beilstein/REAXYS Number:
1754069
MDL number:
MFCD00002789

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产品名称

琥珀酸, crystalline, EMPROVE® ESSENTIAL, ChP, NF, JPE, ACS

SMILES string

OC(=O)CCC(O)=O

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

grade

ACS reagent

agency

ChP
JPE
NF

product line

EMPROVE® ESSENTIAL

assay

99.0-100.5% (HPLC)

form

crystalline
solid

autoignition temp.

470 °C

technique(s)

API processing | cocrystal formation: suitable
API processing | salt formation: suitable

bp

235 °C (lit.)
235 °C/1013 hPa

mp

184-186 °C (lit.)

transition temp

flash point 206 °C

solubility

58 g/L

density

1.56 g/cm3 at 20 °C

anion traces

chloride (Cl-): ≤0.001%
phosphate (PO43-): ≤0.001%
sulfate (SO42-): ≤0.003%

cation traces

As: ≤0.0002%
Fe: ≤5 ppm
heavy metals (as Pb): ≤0.0020%
heavy metals (as Pb): ≤5 ppm

application(s)

liquid formulation
pharma/biopharma processes
pharmaceutical
solid formulation

storage temp.

2-30°C

Quality Level

500

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Application

Succinic acid is a commonly used ingredient in pharmaceutical applications. In such applications it has been used primarily for solid oral dosage forms.

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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