1.02994
山梨醇
liquid, (sorbitol syrup, crystallizing), EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, USP, E 420
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线性分子式:
HOCH2(CHOH)4CH2OH
化学文摘社编号:
分子量:
182.17
E Number:
E420
UNSPSC Code:
12352201
Beilstein/REAXYS Number:
1721899
MDL number:
Quality Segment
agency
BP, ChP, Ph. Eur., USP
vapor density
<1 (vs air)
vapor pressure
<0.1 mmHg ( 25 °C)
product line
EMPROVE® ESSENTIAL
form
liquid, viscous liquid
pH
6 (20 °C in H2O, 50% solution)
mp
98-100 °C (lit.)
density
1.3 g/cm3
application(s)
liquid formulation
pharmaceutical
storage temp.
15-25°C
SMILES string
OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO
InChI
1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1
InChI key
FBPFZTCFMRRESA-JGWLITMVSA-N
General description
Whether suspensions, emulsions or solutions – oral liquid dosage forms offer a number of advantages: They allow for individual dosing, are easy to swallow and are suitable for pediatric or geriatric applications. On the other hand, formulators face considerable challenges concerning solubility, API stability in aqueous systems, or taste that can often make a decisive difference. Our large product portfolio covers all excipients required for oral liquid formulation, as solvents and surfactants, flavors, ph adjustments and buffers, preservatives and viscosity enhancers.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
Application
Sorbitol is a sugar alcohol which is frequently used as sweetener in oral liquid pharmaceutical formulations, as well as bulking agent, sugar substitute or humectant in cosmetics and food and beverage.
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
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