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Merck
CN
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主要文件

1.06666

SAFC

二水柠檬酸三钠,内毒素含量低

EMPROVE® API Ph Eur,BP,JP,USP

别名:

柠檬酸钠三盐基 二水合物, 柠檬酸 三钠盐 二水合物, 柠檬酸三钠 二水合物

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About This Item

线性分子式:
HOC(COONa)(CH2COONa)2 · 2H2O
CAS Number:
分子量:
294.10
Beilstein:
6104939
MDL编号:
UNSPSC代码:
12352302
EC索引号:
200-675-3

Agency

BP
JP
Ph. Eur.
USP

质量水平

产品线

EMPROVE® API

表单

solid

效能

>8000 mg/kg LD50, oral (Rat)

pH值(酸碱度)

7.5-9.0 (25 °C, 50 g/L in H2O)

mp

150 °C (anhydrous substance)
>300 °C (lit.)

溶解性

720 g/L

堆积密度

600 kg/m3

应用

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical
solid formulation

储存温度

2-25°C

SMILES字符串

O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

InChI

1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3

InChI key

NLJMYIDDQXHKNR-UHFFFAOYSA-K

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一般描述

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

tri-Sodium citrate dihydrate is used as anticoagulant in dialysis and plasmapheresis. tri-Sodium citrate dihydrate Emprove® API is manufactured according to ICH Q7 guidelines. An ASMF and US-DMF is available.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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