1.06666
二水柠檬酸三钠，内毒素含量低
EMPROVE® API Ph Eur,BP,JP,USP
别名:
柠檬酸钠三盐基 二水合物, 柠檬酸 三钠盐 二水合物, 柠檬酸三钠 二水合物
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关于此项目
线性分子式:
HOC(COONa)(CH2COONa)2 · 2H2O
化学文摘社编号:
分子量:
294.10
EC Index Number:
200-675-3
UNSPSC Code:
12352302
Beilstein/REAXYS Number:
6104939
MDL number:
Quality Segment
agency
BP, JP, Ph. Eur., USP
product line
EMPROVE® API
form
solid
potency
>8000 mg/kg LD50, oral (Rat)
pH
7.5-9.0 (25 °C, 50 g/L in H2O)
mp
150 °C (anhydrous substance), >300 °C (lit.)
solubility
720 g/L
bulk density
600 kg/m3
application(s)
liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical
solid formulation
storage temp.
2-25°C
SMILES string
O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O
InChI
1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3
InChI key
NLJMYIDDQXHKNR-UHFFFAOYSA-K
General description
We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
Application
tri-Sodium citrate dihydrate is used as anticoagulant in dialysis and plasmapheresis. tri-Sodium citrate dihydrate Emprove® API is manufactured according to ICH Q7 guidelines. An ASMF and US-DMF is available.
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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