Merck
CN
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文件

安全信息

1.07071

SAFC

纽甜

EMPROVE® ESSENTIAL, NF

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所有图片(1)
别名:
N-[N-(3,3-二甲基丁基)-L-α-天冬氨酰]-L-苯丙氨酸1-甲酯
经验公式（希尔记法）:
C20H30N2O5
CAS号:
165450-17-9
分子量:
378.46
Beilstein:
8352678
MDL编号:
MFCD09039056

等级

GMP
Halal
Kosher

质量水平

500

Agency

NF

描述

GMO free

产品线

EMPROVE® ESSENTIAL

形式

fine powder

mp

80-83 °C

application(s)

pharmaceutical
solid formulation

储存温度

15-25°C

SMILES string

COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NCCC(C)(C)C

InChI

1S/C20H30N2O5/c1-20(2,3)10-11-21-15(13-17(23)24)18(25)22-16(19(26)27-4)12-14-8-6-5-7-9-14/h5-9,15-16,21H,10-13H2,1-4H3,(H,22,25)(H,23,24)/t15-,16-/m0/s1

InChI key

HLIAVLHNDJUHFG-HOTGVXAUSA-N

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相关类别

一般描述

As a high-intensity sweetener with an excellent stability and a clean, sugar-like taste profile, neotame is your ideal tool for taste optimization. Due to its exceptional sweetness with a factor 8,000 to 13,000 greater than sucrose and 40-60 greater than aspartame, it is efficient in use and costs.
Neotame is part of our Emprove® Program and offered with extensive documentation facilitating compliance of your pharma product, full supply chain transparency and risk mitigation. The product withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

From orally disintegrating tablets (ODTs), effervescent tablets to syrups and oral films – neotame can be applied to a wide range of pharmaceutical products and enables safe and heat-stable formulations.

特点和优势

  • Excellent sugar-like taste profiles
  • Masking bitter aftertaste and medical off-notes with ease
  • High sweetness potency offers improved cost-efficiency
  • Enhanced stability
  • Non-cariogenic and suitable for diabetics and patients with phenylketonuria

包装

1070711000 / 1 kg / Polyethylene bottle
1070710250 / 250 g / Polyethylene bottle
1070710001 / 3 x 10 g / PE bottles (in cardboard box)

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Strategies for the Development of Safe and Effective Pediatric Formulations

Medicine for children poses unique formulation challenges compared to adults. Consider developmental physiology and age specifics when designing pharmaceuticals. Quality issues can severely impact patient safety. Therefore, excipient quality, supplier selection, and supply chain security are crucial, particularly for pediatric formulations.

相关内容

Pediatric Formulations

Developing formulations specifically for infants and children is increasingly important. To help you master these challenges effectively, we offer an extensive portfolio of well-established high-quality excipients and APIs for pediatric pharmaceutical formulations that are proven in practice.

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