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Merck
CN

1.08720

Thioglycolate Broth

Non animal origin irradiated granulated medium for Microbiological analysis

别名:

Fluid Thioglycolate Medium

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NACRES:
NA.74
UNSPSC Code:
41106200
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sterility

irradiated

form

medium granules

feature

granulated

packaging

pkg of 5 kg

manufacturer/tradename

GranuCult®

pH

6.9-7.3 (25 °C, 29 g/L in H2O)

solubility

29 g/L

application(s)

aseptic process simulation
pharmaceutical

compatibility

stand alone

storage temp.

15-25°C

suitability

anaerobic bacteria (facultative and microaerophilic)

Quality Level

General description

The Granulated media is cold filterable and gamma-irradiated for the microbiological aseptic process simulation (Media Fill Test). The media are supplied in triple-wrapped and cleanroom ready for the ultimate security of aseptic process. It is granulated which guarantees excellent solubility even in cold water. Cold filterability is achieved by extensive testing comprising raw materials, pre-production samples, in-process and end product control

Application

The broth is suitable for media fill tests according to the recommendations of the “FDA Aseptic Guide” in aseptic production lines. The exclusive use of raw materials of non-animal origin allows the elimination of a potential contamination risk with TSE/BSE.

Other Notes

Mode of action: Thioglycolate Broth glucose, peptone from casein and yeast extract provide growth factors necessary for bacterial growth. The reducing agents thioglycolate and L-cystine ensure an anaerobiosis which is adequate even for fastidious anaerobes and prevent the accumulation of peroxides which are lethal to some microorganisms. The sulfhydryl groups of these substances inactivate arsenic, mercury and other heavy metal compounds. Thioglycolate media are thus suitable for the examination of materials which contain heavy metals or heavy metal preservatives.
We offer two media types: the superior granulated GranuCult® and the cost-efficient powdered NutriSelect® culture media, depending on your needs.
The designations basic, plus, or prime are added to indicate the quality control level, from basic quality control to standard QC plus to prime for full regulatory compliance.

Legal Information

GRANUCULT is a registered trademark of Merck KGaA, Darmstadt, Germany
NutriSelect is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 3


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Comparison of Dehydrated Culture Media for Efficient Media Fill Testing by Evaluating Cold Filterability

High quality granulated and ready-to-use culture media irradiated for accurate and reliable aseptic process simulations.

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