Fractogel EMD螯合物(M)

Fractogel^® EMD Chelate combines our tentacle structure with iminodiacetic acid as the metal chelating ligand

Fractogel^® EMD Chelate (M) enables users to:

• Efficiently purify histidine-tagged recombinant proteins
• Coordinate metal ions to non-bonding electron pairs of the amino acid side chains and separate peptides
• Ensure timely and successful startup and operation
• Minimize hydrophobic interactions due to the tentacles technology, resulting in superior selectivity and recovery
• Handle multiple CIP and packing cycles with the chemically and physically robust bead, leading to a longer resin lifetime

Plastic bottle

Appearance: Milky tubid suspension, free from impurities (foreigen particles)
Microscopic evaluation: Uniform spherical particles, no agglomerates, no fines
Cerium: ≤ 10 µg/g
Copper-(II)-binding capacity: 60 - 100 µmol/ml
Extractable matter (water): ≤ 0.05 %
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Particle size (d10): 37 - 45 µm
Particle size (d50): 48 - 60 µm
Particle size (d90): 63 - 77 µm
Colony forming units (TAMC + TYMC): ≤ 100 CFU/ml
Endotoxins: ≤ 1.00 EU/ml
Functional test: passes test
Functional test: Separation of chymotrypsinogen A and myoglobin

FRACTOGEL is a registered trademark of Merck KGaA, Darmstadt, Germany