Merck
CN

1.14894

Millipore

Fractogel EMD SE Hicap (M)

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别名:
Fractogel® EMD SE Hicap (M)

ligand

(Sulfoethyl)

质量水平

描述

strong cation exchanger, suspension in 20% ethanol and 150 mM NaCl (40-90 µm)

无菌性

sterile (Caustic Stable)

产品线

Fractogel®

形式

resin

特殊分析物

MAbs

参数

220 cm/hr flow rate
8 bar max. pressure

基质活性基团

methacrylate

平均粒径

40-90 μm

容量

160 mg binding capacity (lysozyme/ml of resin)

转变温度

flash point 35 °C (calculated)

application(s)

recombinant protein
vaccine development

分离技术

cation exchange
strong cation exchange

储存温度

2-30°C

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Fractogel® EMD DEAE (M)

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Fractogel EMD螯合物(M)

parameter

220 cm/hr flow rate, 8 bar max. pressure

parameter

8 bar max. pressure

parameter

170 cm/hr flow rate, 8 bar max. pressure

parameter

8 bar max. pressure, ~240 cm/hr flow rate

matrix active group

methacrylate

matrix active group

methacrylate

matrix active group

methacrylate

matrix active group

methacrylate

capacity

160 mg binding capacity (lysozyme/ml of resin)

capacity

130 mg binding capacity (lysozyme/ml of resin)

capacity

100 mg binding capacity (BSA/mg of resin)

capacity

~60 mg binding capacity( lysozyme/ml of resin)

separation technique

cation exchange, strong cation exchange

separation technique

cation exchange, strong cation exchange

separation technique

weak anion exchange

separation technique

affinity

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

2-30°C

一般描述

Strong cation exchange Fractogel® resin featuring the tentacle technology, for purification of basic and neutral proteins (e.g. antibodies) and peptides

特点和优势

Fractogel® EMD SE Hicap (M) features include:

  • Tentacle technology provides high yield, selectivity, and focused elution
  • High loading capacity combined with high purity at lower elution volumes
  • Compatibility with 2.5 % (v/v) aqueous benzyl alcohol containing 150 mM NaCl storage solution

包装

  • 1.14894.0100: Fractogel® EMD SE Hicap (M) Resin 100ml
  • 1.14894.0010: Fractogel® EMD SE Hicap (M) Resin 10ml
  • 1.14894.0500: Fractogel® EMD SE Hicap (M) Resin 500ml
  • 1.14894.5000: Fractogel® EMD SE Hicap (M) Resin 5L

Plastic bottle

分析说明

Appearance: Milky turbid suspension,free from impurities(foreign particles)
Microscopic evaluation: Uniform spherical particles,no agglomerates,no fines
Extractable matter (water): ≤ 0.08 %
Cerium: ≤ 20 µg/g
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Particle size (d10): 37 - 45 µm
Particle size (d50): 48 - 60 µm
Particle size (d90): 63 - 77 µm
Colony forming units (TAMC + TYMC): ≤ 100 CFU/ml
Endotoxins: ≤ 1.00 EU/ml
Protein binding capacity (lysozyme): 120 - 160 mg/ml
Functional test (b:a): ≤ 0.20
Functional test: Separation of chymotrypsinogen A and lysozyme

法律信息

FRACTOGEL is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Flame

警示用语:

Warning

危险声明

危险分类

Flam. Liq. 3

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

95.0 °F

闪点(°C)

35 °C


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