产品名称
ESHMUNO HCX, Eshmuno® HCX
ligand
carboxymethyl
phenyl
sulfonate group
sterility
sterile (Caustic Stable)
product line
Eshmuno®
form
resin
specific analyte(s)
MAbs
parameter
1000 cm/hr flow rate
8 bar max. pressure
matrix active group
polymer, polyvinyl ether
capacity
50 mg binding capacity (pIgG/ml of resin)
transition temp
flash point 35 °C (calculated)
application(s)
recombinant protein
vaccine development
separation technique
mixed mode
storage temp.
2-30°C
Quality Level
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Analysis Note
Appearance: Milky cream coloured turbid suspension, free from coarse mechanical impurities.
Microscopic evaluation: Spherical particles, no agglomerates, no fines.
Extractable matter (water): ≤ 0.08 %
Ionic capacity: 170 - 300 µeq/ml
Performance test (chymotrypsinogen): 75 - 95 mS/cm
Performance test (cytochrom C): 55 - 74 mS/cm
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Particle size (50-120 µm): ≥ 80 %
Particle size (d50): 75 - 95 µm
Cerium: ≤ 30 µg/g
Endotoxins: ≤ 1.00 EU/ml
TAMC (total aerobic microbial count): ≤ 100 CFU/ml
TYMC (total yeast and mould count): ≤ 100 CFU/ml
Microscopic evaluation: Spherical particles, no agglomerates, no fines.
Extractable matter (water): ≤ 0.08 %
Ionic capacity: 170 - 300 µeq/ml
Performance test (chymotrypsinogen): 75 - 95 mS/cm
Performance test (cytochrom C): 55 - 74 mS/cm
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Particle size (50-120 µm): ≥ 80 %
Particle size (d50): 75 - 95 µm
Cerium: ≤ 30 µg/g
Endotoxins: ≤ 1.00 EU/ml
TAMC (total aerobic microbial count): ≤ 100 CFU/ml
TYMC (total yeast and mould count): ≤ 100 CFU/ml
Features and Benefits
Eshmuno® HCX chromatography resin enables:
- Greater capacity at high-salt concentrations
- Superior productivity
- Outstanding selectivity
- Rigid base beads for easy packing
- Excellent pressure-flow behavior
- Strong chemical stability
General description
The mixed-mode cation exchanger Eshmuno® HCX media was specifically designed to capture recombinant proteins at higher salt concentrations directly in typical ion exchange and flow-through applications
Packaging
- 1.20087.0100: Eshmuno® HCX Resin 100ml
- 1.20087.0010: Eshmuno® HCX Resin 10ml
- 1.20087.0500: Eshmuno® HCX Resin 500ml
- 1.20087.5000: Eshmuno® HCX Resin 5L
Plastic bottle
Legal Information
Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Flam. Liq. 3
存储类别
3 - Flammable liquids
wgk
WGK 1
flash_point_f
95.0 °F
flash_point_c
35 °C
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