Quality Segment
ligand
(Sulfoisobutyl)
sterility
sterile (Caustic Stable)
product line
Eshmuno®
form
resin
specific analyte(s)
MAbs
parameter
400 cm/hr flow rate, 8 bar max. pressure
matrix active group
polymer, polyvinyl ether
mean particle size
50 μm
capacity
70 mg binding capacity (lysozyme/ml of resin)
transition temp
flash point 35 °C
separation technique
strong cation exchange
storage temp.
2-30°C
General description
Cation exchange resin specifically developed for the flow-through removal of aggregates using frontal chromatography
Features and Benefits
Eshmuno® CP-FT chromatography resin enables:
- Superior flow-through removal of mAb aggregates
- High product recoveries at high mass loadings
- Significant reduction in resin and buffer volume
- Smaller manufacturing footprint (smaller columns, buffer tanks, etc.)
- Low salt process conditions eliminate the need for dilution before subsequent ion exchange steps
- Significant reduction in processing volumes improves virus filtration and ultrafiltration processing economics
- Rigid base bead enables higher flow rates and easier column packing
- Strong chemical stability
- Compatibility with 1 % (v/v) aqueous benzyl alcohol containing 150 mM NaCl and storage solutions 0.1 M NaOH
Packaging
- 1.20093.0100: Eshmuno® CP-FT Resin 100 ml
- 1.20093.0010: Eshmuno® CP-FT Resin 10 ml
- 1.20093.0500: Eshmuno® CP-FT Resin 500 ml
- 1.20093.5000: Eshmuno® CP-FT Resin 5 L
Plastic bottle
Legal Information
Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany
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signalword
Warning
hcodes
Hazard Classifications
Flam. Liq. 3
存储类别
3 - Flammable liquids
wgk
WGK 1
flash_point_f
95.0 °F
flash_point_c
35 °C
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