137141
精胺 四盐酸盐
EMPROVE® EVOLVE
别名:
N,N′-双(3-氨丙基)-1,4-丁二胺 四盐酸盐
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关于此项目
经验公式（希尔记法）:
C10H26N4 · 4HCl
化学文摘社编号:
分子量:
348.18
UNSPSC Code:
12352116
Beilstein/REAXYS Number:
3911771
MDL number:
产品名称
精胺 四盐酸盐, EMPROVE® EVOLVE
InChI
1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
SMILES string
Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN
InChI key
XLDKUDAXZWHPFH-UHFFFAOYSA-N
biological source
synthetic
agency
non-compendial
form
powder
concentration
99.0-101.0 % (w/w) (T)
impurities
≤5000 mg/kg ethanol (HS-GC)
≤890 mg/kg toluene (HS-GC)
mp
310-311 °C (dec.) (lit.)
cation traces
Al: ≤25 mg/kg
Cr: ≤2.5 mg/kg
Cu: ≤25 mg/kg
Fe: ≤130 mg/kg
Ni: ≤2.5 mg/kg
Zn: ≤130 mg/kg
suitability
corresponds for identity (1H-NMR)
application(s)
pharma/biopharma processes
Quality Level
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Biochem/physiol Actions
多胺位点混合型 NMDA 激动-拮抗剂。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。
多胺位点混合型 NMDA 激动-拮抗剂。在高浓度 (1mM) 下观察到神经保护作用，而在低浓度下则观察到神经毒性。它在番木鳖碱-不敏感性甘氨酸位点能够增强激动剂效应。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。
Application
用于从低盐缓冲液中沉淀 DNA。
General description
Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.
M-Clarity Program
As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
M-Clarity Program
As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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