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Merck
CN

MX0HC10FS30

Millistak+® Pod 深层过滤器

X0HC, filtration area 1.1m², Process Scale in NA format Bulk Packaging

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产品名称

Millistak+® Pod 深层过滤器, X0HC, cellulose, L × H × filtration area 62 cm (24.2 in.) × 32 cm (12.5 in.) × 1.1 m2/g, hydrophilic, bulk packaging

material

cellulose , filter aid (inorganic), glass fiber-reinforced polypropylene

description

Secondary clarification of bioreactor harvests, primarily for cell cultures

feature

hydrophilic

manufacturer/tradename

Millistak+®

parameter

1 bar max. differential pressure (15 psid) at 80 °C (Forward), 1 bar max. inlet pressure (15 psi) at 80 °C, 2.1 bar max. differential pressure (30 psid) at 25 °C (Forward), 2.1 bar max. differential pressure (30 psid) at 25 °C (Reverse), 3.5 bar max. inlet pressure (50 psi) at 25 °C

L × H × filtration area

62 cm (24.2 in.) × 32 cm (12.5 in.) × 1.1 m2/g

impurities

0.25 EU/mL bacterial endotoxins (LAL test, Aqueous extraction)

input

sample type liquid

conductivity

19.34-53.2 μS/cm at 25 °C (product water)

Quality Level

400

filter grade

X0HC

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General description

The [TM="Millistak+"] depth filter media is offered in a scalable, disposable format providing greater flexibility because of its unique modular design. The [TM="Millistak+"]MX0HC10FS30 comes in a POD format featuring a 32 cm (H) x 62 cm (L) and a filtration area of 1.1 m2.

This X0HC media series delivers optimal performance through a gradient density matri, ideal for secondary clarification post depth filtration or centrifugation. Can also be utilized in downstream processing steps to protect chromatography columns. applications. [TM="Millistak+"] Pod filters are available in three distinct series of media grades in order to meet your specific needs - DE, CE and HC.

The [TM="Millistak+"] Pod system is ideal for a wide variety of primary and secondary clarification applications, including cell cultures, yeast and E. coli lysates post centrifuge, E. coli refolds, media, vaccines, plasma proteins and sera.

Easy to Use

With the compact, modular design of our [TM="Millistak+"] new Pod system, you can increase productivity and shorten cycle times.

Installation and setup of the Pod system is simple and straightforward. The unique design of the disposable adapters and disposable manifolds makes it easy to connect the Pod filters to rest of the unit operations in the process. The self-contained and disposable nature of the system protects operators from exposure to biohazards and eliminates maintenance as well as cleaning validation requirements.

Application

Secondary clarification of bioreactor harvests, primarily for cell cultures

Features and Benefits

  • Low hold-up volume for greater product yield
  • Broad range of media types offered in single and multilayer products
  • [TM="Millistak+"] HC dual-action media improves prefiltration and compresses clarification
  • Flexible, modular format offers scalability from 5 to 12,000 liters or more
  • Patented disposable design eliminates need for housing, CIP or cleaning validation
  • Self-contained Pod filters protect operators from exposure to biohazards
  • Robust construction is easy to use and set up
  • Smaller footprint facilitates use in tight spaces

Packaging

Bulk Packaging

Preparation Note

Sterilization Method
1 autoclave cycle of 60 min @ 123 ºC

Analysis Note

Product Water Conductivity at 25°C: post autoclave (1 cycle of 60 minutes at 123 °C) and pure water flush of 10 liters per ft2 (100 L/m2) of media surface area

Legal Information

MILLISTAK+ is a registered trademark of Merck KGaA, Darmstadt, Germany

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