76526
L-亮氨酸
certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
别名:
(S)-2-氨基-4-甲基戊酸
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线性分子式:
(CH3)2CHCH2CH(NH2)CO2H
化学文摘社编号:
分子量:
131.17
E Number:
E641
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
200-522-0
MDL number:
Beilstein/REAXYS Number:
1721722
产品名称
L-亮氨酸, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
InChI
1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
InChI key
ROHFNLRQFUQHCH-YFKPBYRVSA-N
SMILES string
CC(C)C[C@H](N)C(O)=O
grade
certified reference material
TraceCERT®
product line
TraceCERT®
analyte chemical class(es)
amino acids, peptides, proteins
manufacturer/tradename
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
color
white
mp
>300 °C (lit.)
application(s)
cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
format
neat
storage temp.
20-25°C
Quality Level
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
L-Leucine is an important and essential branched chain amino acid. It shows activity with the mechanistic target of rapamycin(mTOR) pathway, involved in the synthesis of proteins and satiety.
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.
Check out the entire portfolio of our amino acids certified reference materials (CRM)
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.
Check out the entire portfolio of our amino acids certified reference materials (CRM)
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Legal Information
TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Mullin.EG, et al. et al.
Integrative Weight Management: A Guide for Clinicians (2014)
Fleck M and Petrosyan.MA et al.
Salts of Amino Acids: Crystallization, Structure and Properties (2014)
Michael J Ormsby et al.
Cell reports, 30(7), 2297-2305 (2020-02-23)
Propionic acid (PA) is a bacterium-derived intestinal antimicrobial and immune modulator used widely in food production and agriculture. Passage of Crohn's disease-associated adherent-invasive Escherichia coli (AIEC) through a murine model, in which intestinal PA levels are increased to mimic the
Qian Wang et al.
Journal of the National Cancer Institute, 105(19), 1463-1473 (2013-09-21)
L-type amino acid transporters (LATs) uptake neutral amino acids including L-leucine into cells, stimulating mammalian target of rapamycin complex 1 signaling and protein synthesis. LAT1 and LAT3 are overexpressed at different stages of prostate cancer, and they are responsible for
William I A Haynes et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(11), 4804-4814 (2013-03-15)
The identification of a hyperdirect cortico-subthalamic nucleus connection highlighted the important role of the subthalamic nucleus (STN) in regulating behavior. However, this pathway was shown primarily from motor areas. Hyperdirect pathways associated with cognitive and motivational cortical regions are particularly
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