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Merck
CN

A0575000

盐酸胺碘酮 盐酸盐

European Pharmacopoeia (EP) Reference Standard

别名:

2-丁基-3-苯并呋喃基-4-[2-（二乙氨基）乙氧基]-3,5-二碘苯基酮 盐酸盐, （2-丁基-3-苯并呋喃基） [4-[2-（二乙氨基）乙氧基]-3,5-二碘苯基] 甲酮 盐酸盐

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关于此项目

经验公式（希尔记法）:
C25H29I2NO3 · HCl
化学文摘社编号:
19774-82-4
分子量:
681.77
MDL编号:
MFCD00069204
UNSPSC代码:
41116107
PubChem化学物质编号:
329770619
NACRES:
NA.24

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等级

pharmaceutical primary standard

API类

amiodarone

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

C(=O)(C=1C=2C(OC1CCCC)=CC=CC2)C3=CC(I)=C(OCCN(CC)CC)C(I)=C3.Cl

InChI

1S/C25H29I2NO3.ClH/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3;/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3;1H

InChI key

ITPDYQOUSLNIHG-UHFFFAOYSA-N

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相关类别

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Amiodarone hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

生化/生理作用

Non-selective ion channel blocker. Amiodarone induces an immediate influx of Ca2+ in Saccharomyces cerevisiae, followed by mitochondrial fragmentation and cell death.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

警示用语：

Warning

危险分类

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Irrit. 2 - Lact. - Repr. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Minhui Wang et al.
Pharmacological reports : PR, 66(6), 1022-1030 (2014-12-03)
The antiarrhythmic potential of a novel multichannel blocker CPUY102122 (CY22) was investigated in the present study. The effect of CY22 on rapid delayed rectifier potassium channel current (IKr) was studied using whole-cell patch clamp techniques in Chinese Hamster Ovary cells

实验方案

LC/MS/MS Analysis of Interacting Cardiac Drugs Digoxin, Quinidine, Amiodarone and Verapamil on Titan™ C18

LC/MS/MS Analysis of Interacting Cardiac Drugs Digoxin, Quinidine, Amiodarone and Verapamil on Titan™ C18

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