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线性分子式:
H2NC(=NH)NH(CH2)3CH(NH2)CO2H
化学文摘社编号:
分子量:
174.20
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1725413
产品名称
精氨酸, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1
SMILES string
N[C@@H](CCCNC(N)=N)C(O)=O
InChI key
ODKSFYDXXFIFQN-BYPYZUCNSA-N
grade
pharmaceutical primary standard
API family
arginine
manufacturer/tradename
EDQM
mp
222 °C (dec.) (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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Application
精氨酸EP参考标准品的预期用途是欧洲药典规定的实验室测试。
Biochem/physiol Actions
一氧化氮合成酶的底物，可转化为瓜氨酸和一氧化氮 (NO)。通过与一氧化氮相关的机理诱导胰岛素释放。
General description
本品按现行药典规定交付。该产品的所有支持信息，包括SDS和任何产品信息宣传页均由药典发行机构制定并发布。如需更多信息和支持，请见现行药典的网站。
Other Notes
可能适用相应的销售限制。
Packaging
本品按照现行药典要求提供。有关当前单位数量，请见EDQM 参考目录。
存储类别
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Jurgen R Piet et al.
The Journal of infectious diseases, 209(11), 1781-1791 (2013-12-18)
Streptococcus pneumoniae (pneumococcus) is a major human pathogen causing pneumonia, sepsis and bacterial meningitis. Using a clinical phenotype based approach with bacterial whole-genome sequencing we identified pneumococcal arginine biosynthesis genes to be associated with outcome in patients with pneumococcal meningitis.
Lindsay D Plank et al.
Hepatology (Baltimore, Md.), 61(2), 639-647 (2014-09-13)
Preliminary work suggested that perioperative immunonutrition (IMN) enriched in n-3 fatty acids, arginine, and nucleotides may improve preoperative nutritional status, enhance postoperative recovery, and reduce postoperative infectious complications in patients undergoing liver transplantation (LT). The current study examined these outcomes
Phyllis S Y Chong et al.
Cancer research, 74(11), 3043-3053 (2014-04-02)
PRL-3, an oncogenic dual-specificity phosphatase, is overexpressed in 50% of acute myelogenous leukemia (AML) and associated with poor survival. We found that stable expression of PRL-3 confers cytokine independence and growth advantage of AML cells. However, how PRL-3 mediates these
Jia-Yi Dong et al.
American heart journal, 162(6), 959-965 (2011-12-06)
Previous studies suggest that L-arginine, an amino acid and a substrate of nitric oxide synthase, may have blood pressure (BP)-lowering effect. Because some studies were performed with limited number of patients with hypertension and therefore limited statistical power with sometimes
Kaoru Kumazaki et al.
Nature, 509(7501), 516-520 (2014-04-18)
Newly synthesized membrane proteins must be accurately inserted into the membrane, folded and assembled for proper functioning. The protein YidC inserts its substrates into the membrane, thereby facilitating membrane protein assembly in bacteria; the homologous proteins Oxa1 and Alb3 have
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