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Merck
CN

B0470000

苯哌啶

European Pharmacopoeia (EP) Reference Standard

别名:

1-{1-[4-(4-Fluorophenyl)-4-oxobutyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one

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关于此项目

经验公式(希尔记法):
C22H24FN3O2
化学文摘社编号:
分子量:
381.44
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24
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等级

pharmaceutical primary standard

API类

benperidol

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

Fc1ccc(cc1)C(=O)CCCN2CCC(CC2)[n]3c4c([nH][c]3=O)cccc4

InChI

1S/C22H24FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-10,18H,3,6,11-15H2,(H,24,28)

InChI key

FEBOTPHFXYHVPL-UHFFFAOYSA-N

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Benperidol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Sarah A Eisenstein et al.
Synapse (New York, N.Y.), 67(11), 748-756 (2013-05-08)
Previous PET imaging studies have demonstrated mixed findings regarding dopamine D2/D3 receptor availability in obese relative to nonobese humans. Nonspecific D2/D3 radioligands do not allow for separate estimation of D2 receptor (D2R) and D3 receptor (D3R) subtypes of the D2
Susanne Nikolaus et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 44(4), 618-624 (2003-04-08)
A recent investigation showed that intracerebral radioactivity concentrations can reliably be quantified in vivo with a small-animal PET device. The purpose of the current study was to investigate the binding characteristics of the D(2) receptor radioligand (18)F-(3-N-methyl)benperidol ((18)FMB) in rat
S Dammers et al.
Deutsche medizinische Wochenschrift (1946), 120(50), 1739-1742 (1995-12-15)
A 22-year-old oligophrenic patient had on several occasions over several months been given various neuroleptics (haloperidol, benperidol, levomepromazine) for exacerbations of paranoid schizophrenia. For a few days before hospitalization he had become quiet and withdrawn, but on the day of
Peter Kreuzer et al.
Journal of clinical pharmacology, 52(7), 1090-1097 (2011-10-01)
Hypothermia as an adverse reaction of antipsychotic drug use represents a potentially life-threatening complication. However, the mechanisms by which antipsychotic drugs alter thermoregulatory processes in the human body are far from being fully understood. Here we present a case series
Complete dopamine D2 receptor occupancy without extrapyramidal side effects under benperidol.
Carlos Schönfeldt-Lecuona et al.
Journal of clinical psychopharmacology, 24(1), 97-98 (2004-01-08)

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