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经验公式(希尔记法):
C20H12
化学文摘社编号:
分子量:
252.31
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
205-892-7
Beilstein/REAXYS Number:
1911334
MDL number:
InChI key
TXVHTIQJNYSSKO-UHFFFAOYSA-N
InChI
1S/C20H12/c1-2-8-16-15(7-1)17-9-3-5-13-11-12-14-6-4-10-18(16)20(14)19(13)17/h1-12H
SMILES string
c1ccc2c(c1)c3cccc4ccc5cccc2c5c34
grade
certified reference material
agency
BCR®
manufacturer/tradename
JRC
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
177-180 °C (lit.)
format
neat
storage temp.
2-8°C
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Analysis Note
For more information please see:
BCR050
BCR050
Legal Information
BCR is a registered trademark of European Commission
signalword
Danger
hcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Narumi Sugihara et al.
Toxicology in vitro : an international journal published in association with BIBRA, 21(5), 827-834 (2007-04-06)
The previous studies from our laboratory reported that benzo(a)pyrene (Bap) influenced efflux transport of rhodamine 123 (Rho-123) by induction of P-glycoprotein (P-gp) in Caco-2 cells. The present study investigated whether induction of P-gp and the enhanced efflux transport of Rho-123
W H Houser et al.
Molecular carcinogenesis, 5(3), 232-237 (1992-01-01)
In the rat, expression of the CYP1A1 gene is closely associated with arylhydrocarbon hydroxylase (AHH) enzyme activity. AHH is an inducile enzyme activity known to play an important role in the bioactivation of polycyclic aromatic hydrocarbons (PAHs) to mutagenic and
J A Gibbons et al.
Chemico-biological interactions, 83(3), 203-220 (1992-08-28)
The objective of this study was to examine the potential for a specific ligand of carcinogen binding protein (CBP) to induce changes in the overall character of hepatic microsomal cytochromes P-450 (P450) and to compare potential changes with those induced
D S Vienneau et al.
Cancer research, 55(5), 1045-1051 (1995-03-01)
UDP-glucuronosyltransferases (UGTs) are cytoprotective and may also be genoprotective. Since over 10% of the population have hereditary deficiencies in UGTs, this family of enzymes could constitute an important determinant of susceptibility to chemical carcinogenesis, teratogenesis, and neurodegeneration. Fibroblasts contain Phase
D F Lewis et al.
Toxicology letters, 71(3), 235-243 (1994-05-01)
The present studies were undertaken to provide a rationale for the observation that benzo(a)pyrene and 2-acetylaminofluorene induce the hepatic CYP1A1 protein, whereas their non-carcinogenic isomers benzo(e)pyrene and 4-acetylaminofluorene are, at best, relatively very weak inducers. Using amino acid sequence alignment
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