产品名称
二丙酸倍氯米松（氯地米松）, British Pharmacopoeia (BP) Assay Standard
InChI key
KUVIULQEHSCUHY-XYWKZLDCSA-N
InChI
1S/C28H37ClO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1
SMILES string
CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]12C
grade
pharmaceutical primary standard
API family
beclometasone
form
solid
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
BP
application(s)
pharmaceutical
pharmaceutical small molecule
format
neat
storage temp.
2-8°C
Gene Information
human ... NR3C1(2908)
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Application
Beclometasone (beclomethasone) dipropionate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.
Also used in monographs such as:Beclometasone Pressurised Inhalation Betamethasone and Clioquinol Cream Betamethasone and Clioquinol Ointment Betamethasone Valerate Cream Betamethasone Valerate Ointment Betamethasone Valerate Lotion Beclometasone Inhalation Powder Beclometasone Inhalation Powder, pre-metered Clobetasol Cutaneous Foam Betamethasone Valerate and Coal Tar Paste Clobetasol Cream Beclometasone Cream Clobetasol Shampoo Beclometasone Ointment Clobetasol Scalp Application Clobetasol Ointment Beclometasone Aqueous Nasal Spray
Also used in monographs such as:
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Learn how British Pharmacopoeia (BP) sets the standard by offering quality British Pharmacopoeia Chemical Reference Substances (BPCRS).
Packaging
Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia
signalword
Warning
hcodes
Hazard Classifications
Repr. 2 - STOT RE 2
target_organs
Adrenal gland,Immune system,Bone
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
Dexter J D'Sa et al.
Pharmaceutical research, 31(10), 2716-2723 (2014-04-25)
The techniques available to study formulation stability in pressurized metered dose inhalers (pMDIs) are limited, due to the challenging conditions of working with high pressure propellants. Isothermal microcalorimetry is a valuable tool used to screen and aid in formulation development
Carlos E Rodríguez-Martínez et al.
Advances in therapy, 32(3), 254-269 (2015-03-11)
Allergic rhinitis (AR) is one of the most common chronic respiratory diseases observed in the pediatric population, producing a significant morbidity, and an economic burden due to direct medical costs and indirect costs. Despite the high prevalence of AR in
Bryn Flinders et al.
Analytical and bioanalytical chemistry, 407(8), 2085-2094 (2014-11-05)
Hydrazine-based derivatization reagents have been used to detect the presence of the carbonyl containing glucocorticoid fluticasone proprionate in rat lung tissue by MALDI-MSI. Such reagents also act as a matrix for analysis by MALDI-MS and have been termed "reactive matrices".
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