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Merck
CN

BP1083

异烟肼

British Pharmacopoeia (BP) Reference Standard

别名:

4-吡啶羧酸酰肼, INH, 异烟酸肼, 雷米封

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关于此项目

经验公式（希尔记法）:
C6H7N3O
化学文摘社编号:
54-85-3
分子量:
137.14
NACRES:
NA.24
UNSPSC Code:
41116107
Beilstein/REAXYS Number:
119374
MDL number:
MFCD00006426

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SMILES string

NNC(=O)c1ccncc1

InChI key

QRXWMOHMRWLFEY-UHFFFAOYSA-N

InChI

1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)

grade

pharmaceutical primary standard

API family

isoniazid

form

powder

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

mp

171-173 °C (lit.)

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

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相关类别

Biochem/physiol Actions

针对结核菌的抗生素，抑制分枝菌酸的生物合成。由肝脏 N-乙酰转移酶 (NAT) 和 细胞色素 P450 2E1 (CYP2E1) 代谢形成肝毒素。选择性诱导 CYP2E1 的表达。可逆抑制 CYP2C19 和 CYP3A4 的活性，在临床相关浓度下机械性地灭活 CYP1A2、CYP2A6、CYP2C19 和 CYP3A4。

Application

Isoniazid BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Isoniazid Oral Solution

    • General description

    This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

    Other Notes

    Sales restrictions may apply.

    Packaging

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    pictograms

    Exclamation mark
    GHS07

    signalword

    Warning

    hcodes

    H302,H315

    Hazard Classifications

    Acute Tox. 4 Oral - Skin Irrit. 2

    存储类别

    11 - Combustible Solids

    wgk

    WGK 3

    历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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